The glycosaminoglycans of open wounds.
The glycosaminoglycans of open wounds.
复制标题
开放性伤口的糖胺聚糖。
DOI：
10.1016/0022-4804(80)90055-4
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
R. Donoff
中科院分区：
文献类型：
--
作者：
S. Alexander;R. Donoff
用组织化学方法和选择性酶消化法研究了开放创面中特异性糖胺多聚糖的时程和定位。透明质酸似乎在整个边缘组织中增加，这可能是伤口收缩和上皮迁移的原因。硫酸皮肤素的出现与胶原沉积有关。这项目前的工作还将愈合伤口与其他发育系统进行了比较，在其他发育系统中，糖胺多糖参与了形态发生和细胞分化。
Histochemical methods and selective enzymatic digestions were used to study the time course and location of specific glycosaminoglycans in open rabbit wounds. Hyaluronic acid seems to be increased in whole edge tissue, which may account for wound contraction and epithelial migration. The appearance of dermatan sulfate was correlated with collagen deposition. This current work also compares the healing wound to other developmental systems in which the glycosaminoglycans have been implicated in morphogenesis and cytodifferentiation.