The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions
The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions
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DOI：
10.1038/jid.2013.446
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发表时间：
2014-06-01
影响因子：
6.5
通讯作者：
Naghavi, Mohsen
中科院分区：
文献类型：
--
作者：
Hay, Roderick J.;Johns, Nicole E.;Naghavi, Mohsen
2010年全球疾病负担（GBD）研究估算了1990年至2010年187个国家中15类皮肤病所致的全球疾病负担。对于以下每种疾病，我们进行了系统的文献综述并分析了所得数据：湿疹、银屑病、寻常痤疮、瘙痒症、斑秃、压疮、荨麻疹、疥疮、真菌性皮肤病、脓疱疮、脓肿以及其他细菌性皮肤病、蜂窝织炎、病毒疣、传染性软疣和非黑素瘤皮肤癌。我们使用残疾评估来确定非致命负担。2010年，三种皮肤病——真菌性皮肤病、其他皮肤和皮下疾病以及痤疮——位于全球最常见的10种疾病之列，还有8种位于前50名；这另外5种皮肤问题是瘙痒症、湿疹、脓疱疮、疥疮和传染性软疣。总体而言，在国家层面，皮肤病在残疾生存年数的主要病因中排名第2至第11位。在全球层面，皮肤病是非致命疾病负担的第四大主要病因。由于使用了比以往更多的数据，这些疾病在高收入和低收入国家造成的负担都是巨大的。这些结果强烈表明，迫切需要将皮肤病的预防和治疗纳入未来的全球卫生战略。
The Global Burden of Disease (GBD) Study 2010 estimated the GBD attributable to 15 categories of skin disease from 1990 to 2010 for 187 countries. For each of the following diseases, we performed systematic literature reviews and analyzed resulting data: eczema, psoriasis, acne vulgaris, pruritus, alopecia areata, decubitus ulcer, urticaria, scabies, fungal skin diseases, impetigo, abscess, and other bacterial skin diseases, cellulitis, viral warts, molluscum contagiosum, and non-melanoma skin cancer. We used disability estimates to determine nonfatal burden. Three skin conditions, fungal skin diseases, other skin and subcutaneous diseases, and acne were in the top 10 most prevalent diseases worldwide in 2010, and eight fell into the top 50; these additional five skin problems were pruritus, eczema, impetigo, scabies, and molluscum contagiosum. Collectively, skin conditions ranged from the 2nd to 11th leading cause of years lived with disability at the country level. At the global level, skin conditions were the fourth leading cause of nonfatal disease burden. Using more data than has been used previously, the burden due to these diseases is enormous in both high- and low-income countries. These results argue strongly to include skin disease prevention and treatment in future global health strategies as a matter of urgency.