Wave Transmission in the Pulmonary Arterial System in Disease in Man
Wave Transmission in the Pulmonary Arterial System in Disease in Man
复制标题
人类疾病中肺动脉系统中的波传输
作者：
S. Reuben
本文应用氧化亚氮容积描记技术对21例心脏瓣膜病和肺血栓栓塞症患者进行了常规心导管检查。这些研究是用从肺区记录的高频心音图进行的，以指示右心室射血开始时的肺动脉瓣打开。从肺动脉瓣开放时间到肺毛细血管血流搏动的足点，测量肺动脉至毛细血管血流传导时间。当肺动脉压正常时，传导时间大于160 msec。传导时间缩短提示肺动脉脉搏波传导速度增高，且与肺动脉压水平相关（r = 0.92，P < 0.001）。提示心脏瓣膜病和血栓栓塞性疾病的慢性肺动脉高压患者肺动脉扩张性降低。
Pulmonary capillary blood flow was measured by the nitrous oxide-body plethysmograph technique in 21 patients with valvular heart disease or pulmonary thromboembolism during routine diagnostic cardiac catheterization. The studies were performed with a high-frequency phonocardiogram recorded from the pulmonary area to indicate the pulmonary valve opening at the beginning of right ventricular ejection. The pulmonary artery to capillary flow conduction time was measured from the time of pulmonary valve opening to the foot of the pulmonary capillary flow pulse. The conduction time was greater than 160 msec when the pulmonary artery pressure was normal. The fall in the conduction time in disease indicated elevated pulmonary arterial pulse wave velocity and this correlated well with the level of pulmonary arterial pressure (correlation coefficient 0.92, P < 0.001). This suggests that there is a reduced pulmonary arterial distensibility in the chronic pulmonary hypertension of valvular heart disease and thromboembolic disorders.