Cyclic compressive loading facilitates recovery after eccentric exercise.
Cyclic compressive loading facilitates recovery after eccentric exercise.
复制标题
DOI：
10.1249/mss.0b013e31816c4e12
复制
发表时间：
2008-07
影响因子：
4.1
通讯作者：
Best TM
中科院分区：
文献类型：
--
作者：
Butterfield TA;Zhao Y;Agarwal S;Haq F;Best TM
为了评估按摩疗法的生物学基础，我们开发了一种模拟瑞典按摩的实验方法，并使用控制良好的动物模型评估这种方法对偏心运动引起的肌肉损伤的恢复。对6只新西兰白色家兔的胫骨前肌进行一次损伤性离心收缩。一个肌肉立即进行循环压缩负荷，和对侧作为行使控制。我们发现，开始30分钟的周期性压缩负荷的肌肉，立即一轮离心运动后，促进恢复功能和衰减白细胞浸润。此外，纤维坏死和湿重的组织也减少了压缩负荷。我们的结论是，在兔模型中，运动后立即使肌肉承受压缩负荷会导致肌肉功能的恢复增强和炎症损伤作用的减弱。虽然这些观察结果表明，骨骼肌对周期性压缩力的反应与临床方法（如治疗按摩）产生的压力相似，但需要进一步研究来评估这些发现的转化功效。
To assess the biologic basis of massage therapies, we developed an experimental approach to mimic Swedish massage and evaluate this approach on recovery from eccentric exercise-induced muscle damage using a well-controlled animal model. Tibialis anterior muscles of six New Zealand White rabbits were subjected to one bout of damaging, eccentric contractions. One muscle was immediately subjected to cyclic compressive loads, and the contralateral served as the exercised control. We found that commencing 30 min of cyclic compressive loading to the muscle, immediately after a bout of eccentric exercise, facilitated recovery of function and attenuated leukocyte infiltration. In addition, fiber necrosis and wet weight of the tissue were also reduced by compressive loading. We conclude that subjecting muscle to compressive loads immediately after exercise leads to an enhanced recovery of muscle function and attenuation of the damaging effects of inflammation in the rabbit model. Although these observations suggest that skeletal muscle responds to cyclic compressive forces similar to those generated by clinical approaches, such as therapeutic massage, further research is needed to assess the translational efficacy of these findings.