Cobalt(III)-catalyzed 1,4-addition of C-H bonds of oximes to maleimides
Cobalt(III)-catalyzed 1,4-addition of C-H bonds of oximes to maleimides
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钴(III)催化肟C-H键与马来酰亚胺的1,4-加成
DOI：
10.1039/c7qo00687j
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发表时间：
2018-01-21
影响因子：
5.4
通讯作者：
Wu, Biao
中科院分区：
文献类型：
--
作者：
Chen, Xiangxiang;Ren, Jiangtao;Wu, Biao
报道了肟引导的钴催化芳烃sp(2) C-H键与马来酰亚胺的加成反应，该反应对不同的官能团表现出良好的耐受性，并有效地生成了各种琥珀酰亚胺衍生物。该方案表现出特定的反应活性，仅产生单-C-H键加成产物，不需要外部碱，这表明该钴基催化体系具有独特的反应活性。
Oxime directed cobalt-catalyzed arene sp(2) C-H bond conjugation addition to maleimide was reported, the reaction showed great tolerance to different functional groups, and various succinimide derivatives were efficiently produced. This protocol exhibited specific reactivity with only producing a mono-C-H bond addition product and no external base was needed, which suggested a unique reactivity of this Co-based catalytic system.