Natural rhythm: evidence for occult 40 Hz gamma oscillation in resting motor cortex
Natural rhythm: evidence for occult 40 Hz gamma oscillation in resting motor cortex
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DOI：
10.1016/j.neulet.2004.08.066
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发表时间：
2004-11-23
影响因子：
2.5
通讯作者：
Epstein, CM
中科院分区：
文献类型：
--
作者：
Funk, AP;Epstein, CM
快速伽马振荡，通常在40赫兹，已经在整个大脑中得到证实，包括丘脑、听觉、视觉和运动皮质。伽马节律的作用是难以捉摸的，但几位作者假设，它们有助于将不同的信息“绑定”到单一的连贯感知中，并有助于运动的同步。在骨骼肌中，通常在最大自主收缩时观察到约40赫兹的“Piper节律”，并已被证明与对侧运动皮质有限区域中类似频率的活动相关。伽马节律主要在复杂的皮质活动中被检测到，很少在静止或广泛区域内连贯地记录到。在这里，我们使用双侧半球经颅磁刺激(TMS)来研究正常志愿者对侧肢体非同源肌肉诱发运动电位之间的时间相关性。研究结果表明，大脑两侧大脑半球静息运动皮质存在一种神秘的、同步的40赫兹节律。(C)2004爱思唯尔爱尔兰有限公司。保留所有权利。
Fast gamma oscillations, often at 40 Hz, have been demonstrated throughout the brain including the thalamus, auditory, visual and motor cortices. The function of gamma rhythms is elusive, but several authors have hypothesized that they contribute to the "binding" of diverse information into a single coherent percept, and to the synchronization of movement. In skeletal muscle a "Piper rhythm" around 40Hz is commonly observed during maximal voluntary contraction, and has been shown to correlate with activity of similar frequency in a limited area of contralateral motor cortex. Gamma rhythms are detected primarily during complex cortical activity, and are seldom recorded at rest or coherently over wide areas. Here we use bihemispheric transcranial magnetic stimulation (TMS) to study time-dependent correlations between evoked motor potentials from non-homologous muscles in opposite limbs of normal volunteers. The results suggest the presence of an occult, synchronous 40 Hz rhythm across broad areas of resting motor cortex in both hemispheres. (C) 2004 Elsevier Ireland Ltd. All rights reserved.