Iridium-catalyzed enantioselective [2 + 2 + 2] cycloaddition of diynes and monoalkynes for the generation of axial chiralities
Iridium-catalyzed enantioselective [2 + 2 + 2] cycloaddition of diynes and monoalkynes for the generation of axial chiralities
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DOI：
10.1002/adsc.200600317
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发表时间：
2006-11
影响因子：
5.4
通讯作者：
T. Shibata;Y. Arai;Kyoko Takami;K. Tsuchikama;Takayoshi Fujimoto;Satoshi Takebayashi;K. Takagi
中科院分区：
文献类型：
--
作者：
T. Shibata;Y. Arai;Kyoko Takami;K. Tsuchikama;Takayoshi Fujimoto;Satoshi Takebayashi;K. Takagi
手性铱配合物催化了高对映选择性的分子间[2+2+2]环加成反应。对称和不对称的二炔和具有功能基团的单炔进行反应，得到了各种类型的具有联芳基骨架的轴向手性化合物，具有良好的对映体过量。
A highly enantioselective intermolecular [2+2+2] cycloaddition of alkynes was catalyzed by a chiral iridium complex. Symmetrical and unsymmetrical diynes, and monoalkynes possessing functional group(s) were subjected to the reaction and various types of axially chiral compounds possessing biaryl skeletons were obtained in good to excellent enantiomeric excesses.