Eukaryotic ribosomes can recognize preproinsulin initiation codons irrespective of their position relative to the 5′ end of mRNA
Eukaryotic ribosomes can recognize preproinsulin initiation codons irrespective of their position relative to the 5′ end of mRNA
复制标题
真核核糖体可以识别前胰岛素原起始密码子，无论其相对于 mRNA 5 端的位置如何
作者：
P. Lomedico;S. Mcandrew
The functional assay of a eukaryotic mRNA, into which additional AUG codons have been introduced by in vitro mutagenesis, shows that a translational initiation site need not necessarily be the nearest AUG codon to the 5′ end of a mRNA. Hence, the sequence surrounding the AUG, and not simply its position relative to the 5′ end of mRNA, appears to be important in determining initiation efficiency.
