A comparison of performance-based measures of function in HIV-associated neurocognitive disorders.
A comparison of performance-based measures of function in HIV-associated neurocognitive disorders.
复制标题
HIV 相关神经认知障碍中基于表现的功能测量的比较。
DOI：
10.1007/s13365-011-0023-8
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发表时间：
2011-04
影响因子：
3.2
通讯作者：
Sacktor, Ned
中科院分区：
文献类型：
--
作者：
Gandhi, Nishiena S.;Skolasky, Richard L.;Peters, Katherine B.;Moxley, Richard T.;Creighton, Jason;Roosa, Heidi Vornbrock;Selnes, Ola A.;McArthur, Justin;Sacktor, Ned
本研究的目的是比较HIV相关神经认知障碍（HAND）研究中新的基于表现的功能评估的结果，并将这些功能评估与HAND的特定严重程度相关联。对现有队列中的114例HIV+受试者进行了病史、神经系统检查、神经心理学成套测试以及功能能力的主观和新的客观测量。自我报告的功能表现指标包括卡诺夫斯基表现量表、工具性日常生活活动问卷和身体生活质量指标问卷。较新的客观功能性能评估包括哥伦比亚药物管理和圣地亚哥财务测试。评估这些新的基于性能的功能测量方法预测HAND水平的能力。功能表现的两个客观指标，哥伦比亚药物管理量表和圣地亚哥财务测试，都与HAND的严重程度相关。卡诺夫斯基表现量表和角色和身体生活质量问卷是主观测量指标，也与特定的HAND水平相关。新的功能表现指标可用于客观评价HAND的功能障碍，并验证不同水平的HAND。
The objectives of this study are to compare the results of newer performance-based functional assessments in the study of HIV-associated neurocognitive disorders (HAND) and to correlate these functional assessments with specific levels of severity of HAND. One hundred fourteen HIV+ subjects in an existing cohort were evaluated with a medical history, neurological exam, neuropsychological test battery as well as subjective and novel objective measures of functional abilities. Self-reported measures of functional performance included the Karnofsky Performance Scale, a questionnaire for instrumental activities of daily living, and a questionnaire for physical quality of life measures. The newer objective functional performance assessments in cluded the Columbia Medication Management and the San Diego Finances tests. These newer performance-based measures of function were assessed for their ability to predict level of HAND. The two objective measures of functional performance, The Columbia Medication Management Scale and the San Diego Finances Test, were both associated with levels of severity of HAND. The Karnofsky Performance Scale and the questionnaires for role and physical quality of life were subjective measures that were also associated with specific levels of HAND. Newer measures of functional performance can be used to objectively evaluate functional impairment in HAND and validate different levels of HAND.
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DOI：
10.1017/s1355617704102130
发表时间：
2004-05-01
影响因子：
2.6
作者：
Heaton, RK;Marcotte, TD;Grant, I
通讯作者：
Grant, I
影响因子：
3
作者：
Munakata, Julie;Benner, Joshua S.;Tierce, Jonothan C.
通讯作者：
Tierce, Jonothan C.
DOI：
10.1017/s1355617799566071
发表时间：
1999-09-01
影响因子：
2.6
作者：
Van Gorp, WG;Baerwald, JP;Rabkin, JG
通讯作者：
Rabkin, JG
DOI：
10.2217/hiv.10.23
发表时间：
2010-05-01
期刊：
HIV Therapy
影响因子：
--
作者：
Gandhi, Nishiena S.;Moxley, Richard T.;Sacktor, Ned
通讯作者：
Sacktor, Ned
DOI：
10.1016/j.cogbrainres.2005.05.001
发表时间：
2005-09-01
期刊：
COGNITIVE BRAIN RESEARCH
影响因子：
--
作者：
Graham, DP;Kunik, ME;Snow, AL
通讯作者：
Snow, AL