The tridimensional personality questionnaire in depression: State versus trait issues
The tridimensional personality questionnaire in depression: State versus trait issues
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DOI：
10.1016/0022-3956(95)00041-0
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发表时间：
1996-01-01
影响因子：
4.8
通讯作者：
Dunner, DL
中科院分区：
文献类型：
--
作者：
Chien, AJ;Dunner, DL
本研究的目的是探讨随着时间的推移的稳定性的人格测量定义的Cloninger的三维人格问卷（TPQ）的抑郁症患者。我们对63名参加了三项双盲抗抑郁药试验之一的门诊患者进行了回顾性图表分析。所有受试者在入组和12周试验终止时均完成了TPQ。无论性别或抑郁发作持续时间如何，在抑郁改善的受试者中观察到伤害回避评分的统计学显著性下降。在其他两个维度（新奇寻求和奖励依赖）上没有观察到显著变化。作为一个组，无应答者在任何TPQ维度或分量表中均无统计学显著性降低。虽然新奇的寻求和奖励依赖仍然相对独立的情绪，避免伤害似乎是一个措施，这是在抑郁状态升高，并随着抑郁症的改善而变化。这些发现与其他研究人员的发现一致。
The goal of our study was to examine the stability over time of the personality measures defined by Cloninger's Tridimensional Personality Questionnaire (TPQ) in patients with major depression. We conducted a retrospective chart review of 63 outpatients who bad participated in one of three double-blind antidepressant trials. All subjects had completed the TPQ upon entry and upon termination of the 12-week trials. Statistically significant decrements in harm avoidance scores were observed in those subjects whose depression improved, regardless of gender or duration of presenting depressive episode. No significant changes were observed in the other two dimensions (novelty seeking and reward dependence). Nonresponders as a group had no statistically significant decreases in any TPQ dimension or subscales. While novelty seeking and reward dependence remain relatively independent of mood, harm avoidance appears to be a measure which is elevated during depressive states and which changes with improvement of depression. These findings are consistent with those of other investigators.