The helical ventricular myocardial band: global, three-dimensional, functional architecture of the ventricular myocardium
The helical ventricular myocardial band: global, three-dimensional, functional architecture of the ventricular myocardium
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DOI：
10.1016/j.ejcts.2006.03.011
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发表时间：
2006-04-01
影响因子：
3.4
通讯作者：
Torrent-Guasp, Francisco
中科院分区：
文献类型：
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作者：
Kocica, Mladen J.;Corno, Antonio F.;Torrent-Guasp, Francisco
目前，我们正在目睹新的心脏病诊断工具和治疗方法的出现，但是，在正常和患病心脏结构和功能的基本问题上，没有严肃的科学共识。在过去的十年中，为了建立基本的研究原则，连续组织了三次国际多学科专题讨论会，这将使我们在理解心脏结构和功能方面向前迈出重要的一步。Torrent-Guasp的螺旋心室心肌带是理解心室心肌全局、三维、功能结构的革命性新概念。这个概念定义了主要的累积向量，整合了心室肿块内的组织结构（即形式）和发展的净力（即功能）。在这里，我们揭示了Torrent-Guasp长达半个世纪的功能解剖学研究纲要，根据正在进行的定义综合方法的努力，这将导致对心室形式和功能的新理解，通过连接生物组织的多个尺度，如正在进行的生理组项目所定义的。Torrent-Guasp的螺旋心室心肌带也可能，有希望，允许克服一些困难，在当代努力创建一个全面的心脏数学模型。(c) 2006 Elsevier B.V.版权所有
We are currently witnessing the advent of new diagnostic tools and therapies for heart diseases, but, without serious scientific consensus on fundamental questions about normal and diseased heart structure and function. During the last decade, three successive, international, multidisciplinary symposia were organized in order to setup fundamental research principles, which would allow us to make a significant step forward in understanding heart structure and function. Helical ventricular myocardial band of Torrent-Guasp is the revolutionary new concept in understanding global, three-dimensional, functional architecture of the ventricular myocardium. This concept defines the principal, cumulative vectors, integrating the tissue architecture (i.e. form) and net forces developed (i.e. function) within the ventricular mass. Here we expose the compendium of Torrent-Guasp's half-century long functional anatomical investigations in the light of ongoing efforts to define the integrative approach, which would lead to new understanding of the ventricular form and function by linking across multiple scales of biological organization, as defined in ongoing Physiome project. Helical ventricular myocardial band of Torrent-Guasp may also, hopefully, allow overcoming some difficulties encountered in contemporary efforts to create a comprehensive mathematical model of the heart. (c) 2006 Elsevier B.V. All rights reserved.