Imaging of cardiovascular complications in patients with systemic lupus erythematosus.
Imaging of cardiovascular complications in patients with systemic lupus erythematosus.
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DOI：
10.1177/0961203315588577
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发表时间：
2015-10
期刊：
影响因子：
2.6
通讯作者：
Carr JC
中科院分区：
文献类型：
--
作者：
Lin K;Lloyd-Jones DM;Li D;Liu Y;Yang J;Markl M;Carr JC
在系统性红斑狼疮（SLE）患者的长期生存中，心血管疾病（CVD）是导致死亡的主要原因。近年来，多模态心血管成像方法已被用于心血管风险评估，其已被证明与传统的心血管危险因素和sle特异性疾病相关。定量成像生物标志物可以描述心脏的形态和功能异常，有望为心血管风险分层提供新的见解，并通过评估个体对保护心血管系统或抑制自身免疫反应的治疗反应来指导SLE管理。在这篇综述中，我们将讨论最前沿的心血管成像技术，并讨论这些技术在评估主要SLE相关心脏疾病方面的潜在临床应用和局限性。
In the long-term survivals of patients with systemic lupus erythematosus (SLE), cardiovascular disease (CVD) is a leading cause of death. Recently, multi-modality cardiovascular imaging methods have been adopted for the evaluation of cardiovascular risk, which has shown to be associated with both traditional cardiovascular risk factors and SLE-specific conditions. Quantitative imaging biomarkers, which can describe both morphological and functional abnormalities in the heart, are expected to provide new insights to stratify cardiovascular risks and to guide SLE management by assessing the individual responses to therapies either protecting the cardiovascular system or suppressing the autoimmune reactions. In this review, we will discuss cutting-edge cardiovascular imaging techniques and discuss potential clinical applications and limitations of those techniques for the evaluation of major SLE related heart disorders.