Impact of chitosan/noble metals-based coatings on the plasmochemically activated surface of NiTi alloy
Impact of chitosan/noble metals-based coatings on the plasmochemically activated surface of NiTi alloy
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DOI：
10.1016/j.matchemphys.2020.122931
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发表时间：
2020-07-01
影响因子：
4.6
通讯作者：
Kyziol, K.
中科院分区：
文献类型：
--
作者：
Jablonski, P.;Hebda, M.;Kyziol, K.
等离子化学活化后，将基于壳聚糖的涂层（含有银或金纳米粒子）应用于镍钛诺（NiTi）合金表面，以研究这种功能化对 i）润湿性，ii）耐腐蚀性，iii）金属离子释放和 iv）细胞毒性的影响。基于（1）Ar/O-2/NH3等离子体处理和沉积壳聚糖/AgNPs/vit.C涂层（CS/AgNPs）或（2）Ar/O-2/NH3等离子体处理和沉积壳聚糖/AuNPs涂层（CS/AuNPs）对镍钛诺进行表面改性，导致水接触角减小（亲水性增强），表面粗糙度参数增加，耐腐蚀性能提高，并且具有良好的生物相容性（在人体上得到证明）与未修饰的 NiTi 和壳聚糖层本身相比。所提出的表面功能化可能是一种强大且有前途的策略，可减少病原微生物相关感染，而不会对哺乳动物细胞产生有害影响，从而促进适当的骨整合。
After plasmochemical activation, chitosan-based coatings (containing silver or gold nanoparticles) were applied on nitinol (NiTi) alloy surface to study the effect of this functionalization on i) wettability, ii) corrosion resistance, iii) release of metal ions, and iv) cytotoxicity. Surface modification of nitinol based on (1) Ar/O-2/NH3 plasma treatment and deposition of chitosan/AgNPs/vit.C coating (CS/AgNPs) or (2) Ar/O-2/NH3 plasma treatment and deposition of chitosan/AuNPs coating (CS/AuNPs) resulted in decrease in water contact angle (enhanced hydrophilicity), increase in surface roughness parameters, improvement of corrosion resistance, and good biocompatibility (proved on human osteoblast-like cells in vitro), when compared to both unmodified NiTi and the chitosan layer itself. The proposed surface functionalization can potentially be a powerful and promising strategy for reducing pathogenic microorganism-associated infections without harmful effects towards mammalian cells, thus facilitating proper osseointegration.