HETEROTROPHIC PRODUCTION OF LONG-CHAIN OMEGA-3-FATTY-ACIDS UTILIZING ALGAE AND ALGAE-LIKE MICROORGANISMS
HETEROTROPHIC PRODUCTION OF LONG-CHAIN OMEGA-3-FATTY-ACIDS UTILIZING ALGAE AND ALGAE-LIKE MICROORGANISMS
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DOI：
10.1007/bf02186066
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发表时间：
1994-04-01
影响因子：
3.3
通讯作者：
ABRIL, JR
中科院分区：
文献类型：
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作者：
BARCLAY, WR;MEAGER, KM;ABRIL, JR
虽然在20世纪60年代产生了一些对异养生长微藻以生产色素的兴趣，但直到20世纪80年代，只有最少的商业研究集中在这种类型的生产技术上。最近的发展表明长链ω-3多不饱和脂肪酸在人类饮食中的营养和药物重要性，这激发了人们对微藻作为这些重要化合物来源的兴趣，因为它们是海洋食物网中这些脂肪酸的主要生产者。与室外太阳能池生产相比，食品和药品质量生产可以通过过程控制程度和通过发酵过程实现的无菌性来提高。 所呈现的数据说明，基于微藻的异养生产系统可以表现出比室外池塘系统大2-3个数量级的ω-3脂肪酸生产率。此外，微藻发酵系统报道的长链ω-3脂肪酸生产率比真菌或细菌系统报道的生产率高1-2个数量级。
Although some interest in growing microalgae heterotrophically for the production of pigments was generated in the 1960s, only minimal commercial research was focused on this type of production technology until the 1980s. Recent developments indicating the nutritional and pharmaceutical importance of long chain omega-3 polyunsaturated fatty acids in the human diet have stimulated interest in microalgae as a source of these vital compounds, for they are the primary producers of these fatty acids in marine food webs. Food and pharmaceutical quality production can be enhanced both by the degree of process control and by the sterility achieved through a fermentation process, when compared to outdoor solar pond production. The data presented illustrate that microalgal-based heterotrophic production systems can exhibit omega-3 fatty acid productivities 2-3 orders of magnitude greater than those of outdoor pond systems. Additionally, long chain omega-3 fatty acid productivities reported for the microalgal fermentation systems are 1-2 orders of magnitude greater than productivities reported for fungal or bacterial systems.