Highly efficient construction of spirocyclic chromanone-pyrrolidines via Cu(I)/TF-BiphamPhos-catalyzed asymmetric 1,3-dipolar cycloaddition.
Highly efficient construction of spirocyclic chromanone-pyrrolidines via Cu(I)/TF-BiphamPhos-catalyzed asymmetric 1,3-dipolar cycloaddition.
复制标题
DOI：
10.1039/c1cc13554f
复制
发表时间：
2011-08
影响因子：
4.9
通讯作者：
Tang‐Lin Liu;Zhao-Lin He;Chun‐Jiang Wang
中科院分区：
文献类型：
--
作者：
Tang‐Lin Liu;Zhao-Lin He;Chun‐Jiang Wang
首次报道了一种具有独特的四元螺环和三元螺环立体异构中心的高功能性螺环[4-色满酮-3，3 '-吡咯烷]的合成方法。
A facile synthesis of highly functional spiro-[4-chromanone-3,3'-pyrrolidine] bearing one unique spiro quarternary and three tertiary stereogenic centers is developed in excellent stereoselectivity for the first time.