Pneumothorax in COVID-19 disease- incidence and clinical characteristics

Pneumothorax in COVID-19 disease- incidence and clinical characteristics
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DOI:
10.1186/s12931-020-01504-y
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发表时间:
2020-09-16
影响因子:
5.8
通讯作者:
Criner, Gerard J.
Criner, Gerard J.
中科院分区:
医学2区
文献类型:
--
作者:
Zantah, Massa;Dominguez Castillo, Eduardo;Criner, Gerard J.

文献摘要

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自发性气胸是COVID-19病毒性肺炎的一种罕见并发症。确切的发病率和危险因素仍然未知。在此,我们回顾了因疑似COVID-19肺炎而入住我们机构的3000多名患者中气胸的发生率和结局。方法对我院收治的2019冠状病毒病病例进行回顾性分析。确定诊断为自发性气胸的患者,以计算该事件的发生率。他们的临床特征被彻底记录。收集了有关其临床结局的数据。每个病例都以简要概要的形式介绍。结果2020年3月1日至2020年6月8日,我院共收治疑似COVID 19肺炎患者3368例,鼻咽拭子阳性902例。发现6例COVID-19患者发生自发性气胸(0.66%)。他们的基线成像显示弥漫性双侧毛玻璃样阴影和实变,主要在后肺和外周肺区域。4/6例与机械通气相关。所有患者均需置入胸管。在所有病例中,死亡率(66.6%)与气胸无直接关系。结论自发性气胸是COVID-19病毒性肺炎的一种罕见并发症,可在无机械通气的情况下发生。临床医生应警惕这种并发症的诊断和治疗。
Background Spontaneous pneumothorax is an uncommon complication of COVID-19 viral pneumonia. The exact incidence and risk factors are still unknown. Herein we review the incidence and outcomes of pneumothorax in over 3000 patients admitted to our institution for suspected COVID-19 pneumonia. Methods We performed a retrospective review of COVID-19 cases admitted to our hospital. Patients who were diagnosed with a spontaneous pneumothorax were identified to calculate the incidence of this event. Their clinical characteristics were thoroughly documented. Data regarding their clinical outcomes were gathered. Each case was presented as a brief synopsis. Results Three thousand three hundred sixty-eight patients were admitted to our institution between March 1st, 2020 and June 8th, 2020 for suspected COVID 19 pneumonia, 902 patients were nasopharyngeal swab positive. Six cases of COVID-19 patients who developed spontaneous pneumothorax were identified (0.66%). Their baseline imaging showed diffuse bilateral ground-glass opacities and consolidations, mostly in the posterior and peripheral lung regions. 4/6 cases were associated with mechanical ventilation. All patients required placement of a chest tube. In all cases, mortality (66.6%) was not directly related to the pneumothorax. Conclusion Spontaneous pneumothorax is a rare complication of COVID-19 viral pneumonia and may occur in the absence of mechanical ventilation. Clinicians should be vigilant about the diagnosis and treatment of this complication.