DETECTION OF PITUITARY MICROADENOMAS - COMPARISON OF DYNAMIC KEYHOLE FAST SPIN-ECHO, UNENHANCED, AND CONVENTIONAL CONTRAST-ENHANCED MR-IMAGING
DETECTION OF PITUITARY MICROADENOMAS - COMPARISON OF DYNAMIC KEYHOLE FAST SPIN-ECHO, UNENHANCED, AND CONVENTIONAL CONTRAST-ENHANCED MR-IMAGING
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DOI：
10.2214/ajr.163.3.8079866
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发表时间：
1994-09-01
影响因子：
5
通讯作者：
GEORGE, S
中科院分区：
文献类型：
--
作者：
KUCHARCZYK, W;BISHOP, JE;GEORGE, S
目标。垂体微腺瘤可能无法在常规磁共振图像上检测到。我们用动态锁孔快速自旋回波（kFSE）方法补充传统的非增强和增强磁共振成像，以比较三种不同方法检测微腺瘤的频率。研究对象和方法。连续18例有垂体微腺瘤临床和实验室证据的患者均有未增强的动态kFSE和常规垂体磁共振增强成像。对照组13名无垂体疾病的受试者也进行动态kFSE MR成像。以相同的方式获得所有研究的硬拷贝，然后将患者和对照组的MR图像随机混合。这些研究是由一位不了解受试者临床状况的神经放射学家审查的。注意到垂体局灶性低信号的存在或不存在与微腺瘤的表现一致。18例患者中有13例在动态kFSE图像上发现与微腺瘤外观一致的垂体病变，9例在未增强图像上发现，10例在常规对比增强图像上发现。在4例患者中，仅在动态kFSE图像上检测到微腺瘤。动态kFSE图像显示13例对照受试者中有4例出现病变。动态kFSE磁共振成像是一个有用的补充序列的患者接受磁共振成像，因为垂体内分泌病。它可能会显示出否则无法检测到的病变。
OBJECTIVE. Pituitary microadenomas may not be detected on conventional MR images. We supplemented conventional unenhanced and contrast-enhanced MR imaging with a dynamic keyhole fast spin-echo (kFSE) method in order to compare how frequently a microadenoma could be detected with the three different methods.SUBJECTS AND METHODS. Eighteen consecutive patients with clinical and laboratory evidence of pituitary microadenomas had unenhanced, dynamic kFSE, and conventional contrast-enhanced MR imaging of the pituitary gland. A control group of 13 subjects without pituitary disease also had dynamic kFSE MR imaging. Hard copies of all the studies were obtained in an identical fashion, and then the MR images of the patients and control subjects were randomly mixed. The studies were reviewed by a neuroradiologist who had no knowledge of the clinical status of the subjects. The presence or absence of any pituitary focal hypointensity consistent with the appearance of a microadenoma was noted.RESULTS. A pituitary lesion consistent in appearance with a microadenoma was detected on dynamic kFSE images in 13 of the 18 patients, on unenhanced images in nine patients, and on conventional contrast-enhanced images in 10 patients. In four patients, a microadenoma was detected on dynamic kFSE images only. Dynamic kFSE images showed a lesion in four of the 13 control subjects.CONCLUSION. Dynamic kFSE MR imaging is a useful supplemental sequence in patients undergoing MR imaging because of pituitary endocrinopathy. It may show lesions that would otherwise escape detection.