Middle ear adenomatous neuroendocrine tumors: suggestion for surgical strategy.
Middle ear adenomatous neuroendocrine tumors: suggestion for surgical strategy.
复制标题
中耳腺瘤性神经内分泌肿瘤：手术策略建议
DOI：
10.1016/j.bjorl.2020.05.011
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发表时间：
2022-01
影响因子：
2.2
通讯作者：
Liu, Yuehui
中科院分区：
文献类型：
--
作者：
Xie, Bingbin;Zhang, Shaorong;Dai, Chunfu;Liu, Yuehui
中耳腺瘤神经内分泌肿瘤是具有上皮和神经内分泌分化的极为罕见的肿瘤，占所有中耳和内耳肿瘤的2％，因为这些肿瘤的不同阶段仍然难以捉摸。
这项研究旨在研究中耳腺瘤神经内分泌肿瘤患者的适当手术策略。
六名在北坎大学（Nanchang）的第二附属医院（中国）和Fudan University（中国上海）（中国的耳朵，鼻子和喉咙医院）（中国）的六个患者（在中国的临床特征）中分别接受了63.7个月的临床特征。记录和预后向后。
三名患者接受了鼓膜壁性切除术，包括一名复发性的患者，他们接受了前三名患者的横向临时骨切除；
完全的手术切除为中耳腺瘤神经内分泌肿瘤的患者提供了良好的效果。
Middle ear adenomatous neuroendocrine tumors are extremely rare neoplasms with epithelial and neuroendocrine differentiation, accounting for fewer than 2% of all middle and inner ear tumors. Universal standard surgical procedures for different stages of these tumors remain elusive due to the limitation of the small number of case reports or investigations. This study intends to investigate proper surgical strategies for patients with middle ear adenomatous neuroendocrine tumors. Six patients with middle ear adenomatous neuroendocrine tumors who were treated at the Second Affiliated Hospital of Nanchang University (Nanchang, China) and the Eye, Ear, Nose, and Throat Hospital of Fudan University (Shanghai, China) respectively. Clinical characteristics and management strategies of patients were reviewed. The mean follow-up time was 63.7 months (range, 13–153 months). All the information was collected from medical records and prognosis postoperatively. Three patients underwent canal wall-up tympanomastoidectomy, including one patient with recurrence who underwent a previous tympanotomy; the other three patients underwent lateral temporal bone resection All of these patients were followed up with no evidence of recurrence or metastasis. Patients underwent canal wall-up surgery treatment accompanied with hearing function preservation measurements during follow-up periods. Complete surgical resection provided good results for patients with middle ear adenomatous neuroendocrine tumors. The ossicular chain should be removed. Because of the propensity for local recurrence and invasiveness, as well as regional or distant metastasis of these tumors, it is necessary to schedule long-term follow-up and an observation plan postoperatively.
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影响因子：
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