Expectation of pain replicates the effect of pain in a hand laterality recognition task: Bias in information processing toward the painful side?
Expectation of pain replicates the effect of pain in a hand laterality recognition task: Bias in information processing toward the painful side?
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DOI：
10.1016/j.ejpain.2005.03.009
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发表时间：
2006-04-01
影响因子：
3.6
通讯作者：
Moseley, GL
中科院分区：
文献类型：
--
作者：
Hudson, ML;McCormick, K;Moseley, GL
背景：处于疼痛中或预期疼痛的人，有时会将注意力偏向与疼痛相关的线索。也许他们也偏向他们的注意力对身体的一部分在question.Aim：以确定是否实验引起的疼痛，和疼痛的预期，涉及到信息处理偏向对hand in question.Methods：17名无症状的主题进行了手偏侧识别任务在三个条件：对照组，在肌肉注射高渗盐水引起的手部疼痛期间（疼痛），以及在预期手部疼痛期间，由等渗盐水注射引起（预期）。平均反应时间（RT）确定为三个45秒的时期内的每一个条件和RT之间进行了比较手，条件和时期使用2 × 3 × 3重复测量的多变量方差analysis of variations.Results：有一个手x条件的相互作用和手x条件x时期的相互作用（p < 0.05）。在受试者疼痛或预期疼痛的时期，识别另一只手的RT比对照试验期间长600 ms。在这些时期，RT识别对方的手是类似于600毫秒长于RT识别注射的手，这是一致的跨条件和跨epochs.Conclusions：疼痛和疼痛的预期增加RT识别对方的手。这些发现与信息处理偏向于疼痛或即将疼痛的手是一致的。(c)2005年，国际疼痛研究协会欧洲分会联合会。由爱思唯尔有限公司出版。保留所有权利。
Background: People in pain, or expecting pain, sometimes bias their attention towards pain-relevant cues. Perhaps they also bias their attention towards the body part in question.Aim: To determine if experimentally induced pain, and the expectation of pain, involve an information processing bias towards the hand in question.Methods: Seventeen asymptomatic Subjects performed a hand laterality recognition task during three conditions: control, during hand pain induced by intramuscular injection of hypertonic saline (pain), and during expectation of hand pain, induced by isotonic saline injection (expectation). Mean response time (RT) was determined for three 45 s epochs within each condition and RT was compared between hands, conditions and epochs using a 2 x 3 x 3 repeated measures multivariate analysis of variance.Results: There was a hand x condition interaction and a hand x condition x epoch interaction (p < 0.05 for both). RT to recognise the opposite hand was similar to 600 ms longer during epochs when subjects were in pain or expected pain than during control trials. During those epochs, RT to recognise the opposite hand was similar to 600 ms longer than RT to recognise the injected hand, which was consistent across conditions and across epochs.Conclusions: Both pain and the expectation of pain increased RT to recognise the opposite hand. The findings are consistent with a bias in information processing toward the painful or impending painful hand. (c) 2005 European Federation of Chapters of the International Association for the Study of Pain. Published by Elsevier Ltd. All rights reserved.