Cognitive stimulation therapy (CST) for people with dementiawho benefits most?
Cognitive stimulation therapy (CST) for people with dementiawho benefits most?
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DOI：
10.1002/gps.3823
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发表时间：
2013-03-01
影响因子：
4
通讯作者：
Orrell, M.
中科院分区：
文献类型：
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作者：
Aguirre, E.;Hoare, Z.;Orrell, M.
背景 认知刺激疗法 (CST) 的功效已得到证实，但人们对痴呆症患者的特征知之甚少，这可能预示着对 CST 的更积极反应。本研究旨在调查哪些因素可以预测 CST 的反应。方法 272 名痴呆症参与者参加了为期 7 周的 CST 干预。在治疗前和治疗后进行评估。结果与之前类似的 CST 随机对照试验的结果进行了比较。对 CST 前和 CST 后组的平均分数进行了比较，并检查了预测结果变化的影响因素。结果 CST 可以改善认知能力和生活质量，结果表明 CST 的益处与人们是否服用乙酰胆碱酯酶抑制剂 (AChEI) 药物无关。年龄的增长与认知益处相关，女性也是如此。养老院居民的生活质量比社区居民改善得更多，但社区样本似乎在行为问题方面受益更多。结论 这些结果表明，CST 可以改善痴呆症患者（包括已经服用 AChEI 的患者）的认知和生活质量。年龄较大和女性身份与干预带来的认知益处增加有关。应考虑 CST 的各个方面，这可能会增强男性和 80 岁以下痴呆症患者的益处。版权所有 (c) 2012 John Wiley & Sons, Ltd.
Background The efficacy of cognitive stimulation therapy (CST) has been demonstrated, but little is known about the characteristics of people with dementia, which may predict a more positive response to CST. This study sought to investigate which factors may predict response to CST. Methods Two hundred and seventy-two participants with dementia took part in a 7-week CST intervention. Assessments were carried out pre-treatment and post-treatment. The results were compared with those of a previous comparable CST randomised control trial. A comparison of mean scores pre-CST and post-CST groups was undertaken, and contributing factors that predicted change in outcomes were examined. Results CST improved cognition and quality of life, and the results showed that the benefits of CST were independent of whether people were taking acetylcholinesteraseinhibitor (AChEI) medication. Increasing age was associated with cognitive benefits, as was female gender. Care home residents improved more than community residents on quality of life, but the community sample seemed to benefit more in relation to behaviour problems. Conclusions These results demonstrate that CST improves cognition and quality of life for people with dementia including those already on AChEIs. Older age and being female were associated with increased cognitive benefits from the intervention. Consideration should be given to aspects of CST, which may enhance the benefits for people with dementia who are male and those younger than 80years. Copyright (c) 2012 John Wiley & Sons, Ltd.