Comparison of two positive reinforcing stimuli: pups and cocaine throughout the postpartum period.
Comparison of two positive reinforcing stimuli: pups and cocaine throughout the postpartum period.
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DOI：
10.1037//0735-7044.115.3.683
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发表时间：
2001-06
影响因子：
1.9
通讯作者：
B. Mattson;S. Williams;Jay S. Rosenblatt;Joan I. Morrell
中科院分区：
文献类型：
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作者：
B. Mattson;S. Williams;Jay S. Rosenblatt;Joan I. Morrell
这组实验调查了母性行为表现背后的欲望或动机过程。地点偏好范式被用来同时研究可卡因和幼崽对母体哺乳母体的强化特性。这些修改使作者能够评估哪种刺激，无论是10 mg/kg的S.C.注射可卡因或3只幼鼠，有最强的强化价值。在产后第10天和第16天，母犬更喜欢与可卡因线索相关的房间，而在产后第8天测试的母亲更喜欢与小狗线索相关的房间。总体而言，数据揭示了产后测试期间与表现出的对可卡因或幼崽的偏好之间的相互作用。进一步的测试将研究每个刺激的食欲过程背后的神经回路。
This set of experiments investigated the appetitive or motivational processes underlying the performance of maternal behavior. The place preference paradigm was adapted to simultaneously investigate the reinforcing properties of cocaine and pups for maternal, lactating dams. These modifications allowed the authors to assess which stimulus, either a 10 mg/kg s.c. injection of cocaine or 3 pups, had the strongest reinforcing value. At Postpartum Days 10 and 16, the dams preferred the cocaine cue-associated chamber, whereas the dams tested at Postpartum Day 8 preferred the pup cue-associated chamber. Overall, the data revealed an interaction between the postpartum period at testing and the exhibited preference for cocaine or pups. Further testing will investigate the neural circuitry underlying the appetitive processes of each stimulus.