Recommendations for preclinical research in hemorrhagic transformation.

Recommendations for preclinical research in hemorrhagic transformation.
复制标题

DOI:
10.1007/s12975-012-0222-5
复制
发表时间:
2013-06
影响因子:
6.9
通讯作者:
Ergul, Adviye
Ergul, Adviye
中科院分区:
医学1区
文献类型:
--
作者:
Fagan, Susan C.;Lapchak, Paul A.;Liebeskind, David S.;Ishrat, Tauheed;Ergul, Adviye

文献摘要

参考文献

被引文献

相似文献

出血性转化(HT)是缺血性脑卒中的重要并发症,是导致急性再灌注治疗相关死亡的主要原因。尽管许多重要的出版物都讨论了缺血性卒中的临床前模型,但目前还没有关于开展旨在了解HT机制和后果的研究的建议。本综述的目的是介绍用于羟色胺研究的各种模型,临床相关因素,以及在临床前研究中已知的影响羟色胺定量的实验变量。最后,对HT的临床前研究提出了建议。
Hemorrhagic transformation (HT) is an important complication of ischemic stroke and is responsible for most of the mortality associated with acute reperfusion therapy. Although many important publications address the preclinical models of ischemic stroke, there are no current recommendations on the conduct of research aimed at understanding the mechanisms and consequences of HT. The purpose of this review is to present the various models used in HT research, the clinical correlates, and the experimental variables known to influence the quantitation of HT in preclinical investigation. Lastly, recommendations for the conduct of preclinical research in HT are provided.
DOI: 10.1097/00004647-199906000-00005
发表时间: 1999-06-01
影响因子: 6.3
作者:
Heo, JH;Lucero, J;del Zoppo, GJ
通讯作者: del Zoppo, GJ
DOI: 10.1179/016164103101201526
发表时间: 2003-06-01
影响因子: 1.9
作者:
Fagan, SC;Nagaraja, TN;Knight, RA
通讯作者: Knight, RA
DOI: 10.1056/nejmoa0804656
发表时间: 2008-09-25
影响因子: 158.5
作者:
Hacke, Werner;Kaste, Markku;Toni, Danilo
通讯作者: Toni, Danilo
DOI: 10.1161/01.str.28.11.2296
发表时间: 1997-11-01
期刊: STROKE
影响因子: 8.3
作者:
Choudhri, TF;Hoh, BL;Pinsky, DJ
通讯作者: Pinsky, DJ
DOI: 10.1097/hjh.0b013e3280149708
发表时间: 2007-04-01
影响因子: 4.9
作者:
Elewa, Hazem F.;Kozak, Anna;Fagan, Susan C.
通讯作者: Fagan, Susan C.