A Case of Myelolipoma with Bilateral Adrenal Hyperaldosteronism Cured after Unilateral Adrenalectomy
A Case of Myelolipoma with Bilateral Adrenal Hyperaldosteronism Cured after Unilateral Adrenalectomy
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DOI：
10.2169/internalmedicine.51.5777
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发表时间：
2012-01-01
影响因子：
1.2
通讯作者：
Nakao, Kazuwa
中科院分区：
文献类型：
--
作者：
Inuzuka, Megumi;Tamura, Naohisa;Nakao, Kazuwa
骨髓脂肪瘤是一种由脂肪和造血组织组成的肾上腺肿瘤，很少与原发性醛固酮增多症（PA）相关。在这里，我们报告一个骨髓脂肪瘤与PA。肾上腺静脉取样和病理分析证实双侧肾上腺醛固酮分泌过多，但PA在手术切除单侧肾上腺和不产生醛固酮的骨髓脂肪瘤后临床治愈。这表明骨髓脂肪瘤可能会释放一些刺激肾上腺醛固酮生成的因子，但需要进一步研究。肥胖相关的醛固酮增多症可能部分参与了本例高血压的发生。
Myelolipomas are adrenal tumors composed of both adipose and hematopoietic tissues which are rarely associated with primary aldosteronism (PA). Here, we report a case of myelolipoma associated with PA. Aldosterone hypersecretion from bilateral adrenal glands had been confirmed by adrenal venous sampling and pathological analyses, but PA was clinically cured after surgical removal of the unilateral adrenal gland together with the myelolipoma that was not producing aldosterone. It is suggested that myelolipomas may release some factors which stimulate aldosterone production in adrenal glands, although further investigation is necessary. Obesity-related hyperaldosteronism might in part participate in generation of hypertension in the present case.