The Japan Monkey Centre Primates Brain Imaging Repository for comparative neuroscience: an archive of digital records including records for endangered species
The Japan Monkey Centre Primates Brain Imaging Repository for comparative neuroscience: an archive of digital records including records for endangered species
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DOI：
10.1007/s10329-018-0694-3
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发表时间：
2018-10
期刊：
影响因子：
1.7
通讯作者：
Tomoko Sakai;J. Hata;Hiroki Ohta;Yuta Shintaku;Naoto Kimura;Yuki Ogawa;Kazumi Sogabe;S. Mori;H. Okano;Y. Hamada;S. Shibata;Hideyuki Okano;K. Oishi
中科院分区：
文献类型：
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作者：
Tomoko Sakai;J. Hata;Hiroki Ohta;Yuta Shintaku;Naoto Kimura;Yuki Ogawa;Kazumi Sogabe;S. Mori;H. Okano;Y. Hamada;S. Shibata;Hideyuki Okano;K. Oishi
磁共振成像（MRI）和计算分析技术的进步使得能够以三维电子格式对各种灵长类动物的大脑进行比较。比较研究的结果提供了有关灵长类动物的共同特征和神经解剖学物种特异性特征的信息。对各种非人类灵长类动物的研究对于理解这些特征非常重要，但大多数 MRI 比较研究都是基于实验灵长类动物，例如普通狨猴、猕猴和黑猩猩。一个主要障碍是缺乏包含非实验灵长类动物大脑核磁共振成像的数据库。为了促进比较神经解剖学和大脑进化领域的科学发现，我们启动了一个合作项目，开发一个使用离体 MRI 获得的非人类灵长类大脑图像的开放资源存储库。作为最初的开放资源，我们在这里发布了从 12 个物种获得的结构 MRI 和扩散张量图像的集合：侏儒狨猴、猫头鹰猴、白额卷尾猴、食蟹猕猴、日本猕猴、帽子猕猴、托克猕猴、赛克斯猴、红尾猴、施密特长臂猴、德布拉扎长臂猿和拉尔长臂猿。来自 12 个物种的 16 个死后大脑样本储存在日本猴子中心 (JMC)，使用 9.4-T MRI 扫描仪进行扫描，并通过 JMC 合作研究计划 (http://www.j-monkey.jp/BIR/index_e.html) 提供。 JMC 灵长类脑成像存储库的预期重大贡献包括 (1) 用于比较神经科学研究的资源，(2) 以永久数字形式保存各种灵长类动物的大脑，包括濒危物种的大脑，(3) 与以前的 MRI 图集相比，用于识别神经解剖学特征的分辨率更高的资源，(4) 用于优化大型固定大脑扫描方法的资源，以及 (5) 兽医神经放射学参考。除了这些贡献之外，还预计用户发起的研究项目。
Advances in magnetic resonance imaging (MRI) and computational analysis technology have enabled comparisons among various primate brains in a three-dimensional electronic format. Results from comparative studies provide information about common features across primates and species-specific features of neuroanatomy. Investigation of various species of non-human primates is important for understanding such features, but the majority of comparative MRI studies have been based on experimental primates, such as common marmoset, macaques, and chimpanzee. A major obstacle has been the lack of a database that includes non-experimental primates’ brain MRIs. To facilitate scientific discoveries in the field of comparative neuroanatomy and brain evolution, we launched a collaborative project to develop an open-resource repository of non-human primate brain images obtained using ex vivo MRI. As an initial open resource, here we release a collection of structural MRI and diffusion tensor images obtained from 12 species: pygmy marmoset, owl monkey, white-fronted capuchin, crab-eating macaque, Japanese macaque, bonnet macaque, toque macaque, Sykes’ monkey, red-tailed monkey, Schmidt’s guenon, de Brazza’s guenon, and lar gibbon. Sixteen postmortem brain samples from the 12 species, stored in the Japan Monkey Centre (JMC), were scanned using a 9.4-T MRI scanner and made available through the JMC collaborative research program ( http://www.j-monkey.jp/BIR/index_e.html ). The expected significant contributions of the JMC Primates Brain Imaging Repository include (1) resources for comparative neuroscience research, (2) preservation of various primate brains, including those of endangered species, in a permanent digital form, (3) resources with higher resolution for identifying neuroanatomical features, compared to previous MRI atlases, (4) resources for optimizing methods of scanning large fixed brains, and (5) references for veterinary neuroradiology. User-initiated research projects beyond these contributions are also anticipated.