Synergistic interactions of T4 early proteins concerned with their binding to DNA.
Synergistic interactions of T4 early proteins concerned with their binding to DNA.
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T4 早期蛋白的协同相互作用与其与 DNA 的结合有关。
DOI：
10.1073/pnas.71.6.2226
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发表时间：
1974
影响因子：
11.1
通讯作者：
J. M. Buchanan
中科院分区：
文献类型：
--
作者：
W. Huang;J. M. Buchanan
在适当的条件下，T4噬菌体产生的19种不同的早期蛋白质以不同的亲和力结合DNA。它们包括与T4 DNA代谢有关的基因产物，如DNA阴性、DNA停滞和DNA延迟基因，以及其他作用尚未确定的基因。可识别的DNA结合蛋白是基因43、rIIA、46、30、39、52、betagt、32和内部蛋白III的产物。在某些情况下，蛋白质-蛋白质相互作用参与DNA-蛋白质复合物的形成。
Under appropriate conditions, 19 distinct early proteins produced by bacteriophage T4 bind DNA with various affinities. They include products of genes that have been implicated in T4 DNA metabolism, such as DNA negative, DNA arrest, and DNA delay genes, and others whose roles have not yet been defined. The identifiable DNA-binding proteins are the products of genes 43, rIIA, 46, 30, 39, 52, betagt, 32, and internal protein III. In some cases, protein-protein interactions are involved in the formation of the DNA-protein complexes.