Murine coronavirus infection: A paradigm for virus induced demyelinating disease
Murine coronavirus infection: A paradigm for virus induced demyelinating disease
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DOI：
10.1016/s0966-842x(97)81768-4
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发表时间：
1997-01-01
影响因子：
15.9
通讯作者：
Buchmeier, MJ
中科院分区：
文献类型：
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作者：
Lane, TE;Buchmeier, MJ
人类的多种神经系统疾病，包括多发性硬化症（MS），都被认为是由病毒引起的。动物模型的使用提供了对疾病过程中涉及的潜在机制的见解。啮齿动物中的鼠冠状病毒诱导的脱髓鞘疾病是人类脱髓鞘疾病的一种这样的模型。
A variety of neurological diseases in humans, including multiple sclerosis (MS), have been postulated to have a viral etiology. The use of animal models provides insights into potential mechanism(s) involved in the disease process. The murine coronavirus-induced demyelinating disease in rodents is one such model for demyelinating disease in humans.