Bidirectional movement of actin filaments along tracks of heavy meromyosin and native thick filaments
Bidirectional movement of actin filaments along tracks of heavy meromyosin and native thick filaments
复制标题
肌动蛋白丝沿着重肌球蛋白和天然粗丝的轨迹双向运动
作者：
Y. Toyoshima
摘要 通过体外运动测定，根据肌动蛋白运动的方向研究了肌球蛋白分子的灵活性。肌动蛋白丝可以在硝化纤维表面上形成的重肌球蛋白的轨道上双向移动，此外，还可以沿着穿过其中央裸露区域的天然粗丝移动。这些观察结果表明肌球蛋白分子在与肌动蛋白丝相互作用时具有相当大的灵活性。
Summary Flexibility of the myosin molecule was studied by an in vitro motility assay in terms of the direction of actin movement. Actin filaments can move in both directions on tracks of heavy meromyosin made on a nitrocellulose surface, and, furthermore, along the native thick filaments passing over their central bare zone. These observations indicate that the myosin molecule has a considerable flexibility in interacting with actin filaments.