Objective and subjective sleep quality in premenopausal, perimenopausal, and postmenopausal women in the Wisconsin Sleep Cohort Study.
Objective and subjective sleep quality in premenopausal, perimenopausal, and postmenopausal women in the Wisconsin Sleep Cohort Study.
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DOI：
10.1093/sleep/26.6.667
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发表时间：
2003-09
期刊：
影响因子：
5.6
通讯作者：
T. Young;D. Rabago;A. Zgierska;Diane Austin;Finn Laurel
中科院分区：
文献类型：
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作者：
T. Young;D. Rabago;A. Zgierska;Diane Austin;Finn Laurel
研究目的客观评价绝经前、围绝经期和绝经后妇女的睡眠质量。设计观察性流行病学研究。以社区为基础。对象概率样本589绝经前，围绝经期，绝经后妇女从国家雇员的记录招募。干预措施测量和结果月经状态由月经史、手术史和激素替代疗法的使用决定。睡眠质量是通过实验室多导睡眠描记仪和自我报告的睡眠问题来客观测量的。线性和逻辑回归用于估计调整潜在混杂因素后的相关性。目的：与绝经前妇女相比，围绝经期或绝经后妇女的睡眠质量并不差。而绝经后妇女的睡眠时间明显延长（388 min vs 374 min，P = 0.05），3/4期的睡眠时间明显延长（16% vs 13%，P <0.001）。月经状态与自我报告的睡眠不满意度中度相关，但与失眠或嗜睡症状不一致。结论：绝经与多导睡眠图测量的睡眠质量下降无关。虽然绝经前后的妇女，相对于绝经前的妇女，对自己的睡眠不太满意，绝经并不是一个强有力的预测特定的睡眠障碍症状。在排除潜在的睡眠障碍之前，中年女性睡眠异常的症状和体征不应该主要归因于更年期。
STUDY OBJECTIVE Assess objectively measured sleep quality in premenopausal, perimenopausal, and postmenopausal women. DESIGN Observational epidemiology study. SETTING Community-based. PARTICIPANTS Probability sample of 589 premenopausal, perimenopausal, and postmenopausal women recruited from state employee records. INTERVENTIONS None. MEASUREMENTS AND RESULTS Menopausal status was determined by menstrual history, surgical history, and use of hormone replacement therapy. Sleep quality was objectively measured by full in-laboratory polysomnography and by self-reported sleep problems. Linear and logistic regression were used to estimate associations adjusted for potential confounding factors. OBJECTIVE Sleep quality was not worse in perimenopausal or postmenopausal women, compared with premenopausal women. To the contrary, postmenopausal woman had more deep sleep (16% vs 13% stages 3/4, P < 0.001) and significantly longer total sleep time (388 minutes vs 374 minutes, P = 0.05). Menopausal status was moderately related to self-reported dissatisfaction with sleep but was not consistently associated with symptoms of insomnia or sleepiness. CONCLUSIONS Menopause is not associated with diminished sleep quality measured by polysomnography. Although perimenopausal and postmenopausal women, relative to premenopausal women, were less satisfied with their sleep, menopause was not a strong predictor of specific sleep-disorder symptoms. Symptoms and signs of sleep abnormalities in midlife women should not be attributed primarily to menopause before ruling out underlying sleep disorders.