Mutual suppression in the 6 kHz region of sensitive chinchilla cochleae
Mutual suppression in the 6 kHz region of sensitive chinchilla cochleae
复制标题
DOI：
10.1121/1.2718398
复制
发表时间：
2007-05-01
影响因子：
2.4
通讯作者：
Rhode, William S.
中科院分区：
文献类型：
--
作者：
Rhode, William S.
在敏感的灰鼠耳蜗的6-9 kHz区域中，使用具有接近或优于60 dB的增益的位移测量干涉仪测量用于单音和双音抑制（2 TS）范例的基底膜（BM）振动。根据以往对基底膜振动的研究，BM和听神经（AN）2 TS反应存在三个显著差异：（1）BM调谐曲线尾部的抑制阈值远高于听神经（AN），（2）AN的抑制率显著高于BM，（3）BM的抑制率显著高于AN。（3）低频抑制器的振动幅度总是大于单音位移，这使得无法解释AN中的2 TS速率抑制。本研究的结果消除了前两个差异，而第三个仍然存在。抑制幅度大于40 dB和抑制率大于2.5 dB/dB的低频抑制器。耳蜗的增益和非线性与2 TS特性之间的相关性表明，当敏感耳蜗进行研究。BM和AN行为之间的第三个差异可以严格地是内毛细胞的高通滤波器特性的函数。(C)2007年，美国声学学会。
Basilar membrane (BM) vibration was measured using a displacement measuring interferometer for single-tone and two-tone suppression (2TS) paradigms in the 6-9 kHz region of sensitive chinchilla cochleae that had gains near or better than 60 dB. Based on prior studies of basilar membrane vibration, three significant differences remain between BM and auditory nerve (AN) 2TS responses: (1) suppression thresholds in the tail of tuning curves were much higher in BM than the auditory nerve (AN); (2) rates of suppression were significantly higher in AN than BM; and (3) the amplitude of vibration with low-frequency suppressors was always greater than the single-tone displacement rendering it impossible to explain 2TS rate suppression in the AN. The first two differences are eliminated by the results of the present study while the third remains. Suppression amplitudes greater than 40 dB and rates of suppression larger than 2.5 dB/dB were found for low-frequency suppressors. A correlation between both the gain and nonlinearity of the cochlea and 2TS properties indicates that when sensitive cochleae are studied. The third difference between BM and AN behavior could be strictly a function of the high-pass filter characteristic of the inner hair cells. (C) 2007 Acoustical Society of America.