Lesions of endodontic origin and risk of coronary heart disease
Lesions of endodontic origin and risk of coronary heart disease
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DOI：
10.1177/154405910608501104
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发表时间：
2006-11-01
影响因子：
7.6
通讯作者：
Beck, J. D.
中科院分区：
文献类型：
--
作者：
Caplan, D. J.;Chasen, J. B.;Beck, J. D.
关于牙髓病对全身健康影响的流行病学研究很少。本研究评估了VA牙科纵向研究中708名男性参与者中，牙髓起源的放射学明显病变是否与冠心病（CHD）的发展相关。在基线和每三年长达32年，参与者（谁不是VA患者）接受完整的医疗和牙科检查，包括全口X光片。考克斯回归模型估计的发病率之间的关系病变的牙髓起源和时间冠心病诊断。在40岁的人群中，没有观察到统计学上的显著关联。这些发现与提示慢性牙周炎与CHD发展之间关系的研究一致，特别是在年轻男性中。
A paucity of epidemiologic research exists regarding systemic health consequences of endodontic disease. This study evaluated whether incident radiographically evident lesions of endodontic origin were related to development of coronary heart disease (CHD) among 708 male participants in the VA Dental Longitudinal Study. At baseline and every three years for up to 32 years, participants (who were not VA patients) received complete medical and dental examinations, including full-mouth radiographs. Cox regression models estimated the relationship between incident lesions of endodontic origin and time to CHD diagnosis. Among those 40 years old, no statistically significant association was observed. These findings are consistent with research that suggests relationships between chronic periodontal inflammation and the development of CHD, especially among younger men.