Programmed Self-Assembly Systems of Amphiphilic Random Copolymers into Size-Controlled and Thermoresponsive Micelles in Water
Programmed Self-Assembly Systems of Amphiphilic Random Copolymers into Size-Controlled and Thermoresponsive Micelles in Water
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DOI：
10.1021/acs.macromol.7b01918
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发表时间：
2018-01-23
期刊：
影响因子：
5.5
通讯作者：
Terashima, Takaya
中科院分区：
文献类型：
--
作者：
Imai, Shota;Hirai, Yuji;Terashima, Takaya
我们报告程序自组装系统，两亲性无规共聚物轴承亲水性聚（乙二醇）（PEG）和疏水性烷基侧基到大小控制和温度响应胶束在水中。该系统提供了同时和精确的控制的大小，聚集数，和浊点（Cp）的胶束在水中的一级结构（侧链烷基，组成，和链长），这是编程的共聚物。通常，带有PEG和烷基侧基（丁基、辛基、十二烷基和十八烷基）的无规共聚物普遍会在水中诱导分子间自组装，产生均匀尺寸的胶束（
We report programmed self-assembly systems of,amphiphilic random copolymers bearing hydrophilic poly(ethylene glycol) (PEG) and hydrophobic alkyl pendants into size-controlled and thermoresponsive micelles in water. This system affords simultaneous and precise control of the size, aggregation numbers, and cloud point (Cp) of micelles in water by primary structure (pendant alkyl groups, composition, and chain length) that is programmed in the copolymers. Typically, random copolymers bearing PEG and alkyl pendants (butyl, octyl, dodecyl, and octadecyl groups) universally induce intermolecular self-assembly in water to produce uniform size micelles (