Antineoplastic chemotherapy of the older cancer patient
Antineoplastic chemotherapy of the older cancer patient
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DOI：
10.1016/s0889-8588(05)70284-7
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发表时间：
2000-02-01
影响因子：
2.4
通讯作者：
Corcoran, MB
中科院分区：
文献类型：
--
作者：
Balducci, L;Corcoran, MB
如果采取适当的措施，癌症化疗对于老年患者可能是有效且安全的。化疗剂量应根据患者的肾小球滤过率进行调整，并且在治疗期间应维持患者的血红蛋白水平。对于70岁以上且正在接受中等毒性化疗的患者，应使用生长因子。粘膜炎的风险随着患者年龄的增长而增加，因此在并发症出现的最初迹象时积极治疗非常重要。
Cancer chemotherapy may be effective and safe in older patients if some proper provisions are made. Doses of chemotherapy should be adjusted to the patient's glomerular filtration rate, and his or her hemoglobin should be maintained for the duration of the therapy. For patients who are 70 years of age or older and who are receiving moderately toxic chemotherapy, growth factors should be used. The risk of mucositis increases with the age of the patient, so it is important to treat it aggressively at the first signs of the complication.