Transcranial Histotripsy Therapy: A Feasibility Study
Transcranial Histotripsy Therapy: A Feasibility Study
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DOI：
10.1109/tuffc.2014.2947
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发表时间：
2014-04-01
影响因子：
3.6
通讯作者：
Cain, Charles A.
中科院分区：
文献类型：
--
作者：
Kim, Yohan;Hall, Timothy L.;Cain, Charles A.
本研究探讨了通过完整的人类颅骨帽进行非侵入性组织摧毁治疗的可行性。还评价了使用极短脉冲的治疗的消融精度。自制了一个500 kHz的32单元聚焦半球阵列，它可以在焦点处产生高的瞬时峰值稀疏压力（p-）（理论上在自由场超过100 MPa）
This study investigates the feasibility of performing noninvasive histotripsy therapy through an intact human skull cap. The ablation precision of the therapy using extremely short pulses was also evaluated. A 500-kHz 32-element focused hemispherical array was fabricated in-house; it can generate high instantaneous peak rarefactional pressures (p-) at the focus (theoretically over 100 MPa in free field) with pulses