Polarographic measurements of oxygen tension in human glioma and surrounding peritumoural brain tissue
Polarographic measurements of oxygen tension in human glioma and surrounding peritumoural brain tissue
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DOI：
10.1016/s0167-8140(99)00121-8
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发表时间：
1999-11-01
影响因子：
5.7
通讯作者：
Knisely, JPS
中科院分区：
文献类型：
--
作者：
Collingridge, DR;Piepmeier, JM;Knisely, JPS
本研究量化了脑胶质瘤及周围脑组织中pO(2)的空间分布。胶质瘤和肿瘤周围的大脑都含有氧张力低于2.5 mmHg的区域。以缺氧为目标提高治疗效果的方法可能在这种疾病的治疗中发挥重要作用。1999爱思唯尔科学爱尔兰有限公司版权所有。
This study quantifies the spatial distribution of pO(2) in glioma and in the surrounding brain tissue. Both glioma and peritumoural brain contain regions at oxygen tensions less than 2.5 mmHg. Modalities targeting hypoxia to improve the efficacy of therapy may have an important role in the management of this disease. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.