Tooth-derived bone graft material.
Tooth-derived bone graft material.
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DOI：
10.5125/jkaoms.2013.39.3.103
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发表时间：
2013-06
影响因子：
1
通讯作者：
Mitsugi M
中科院分区：
文献类型：
--
作者：
Kim YK;Lee J;Um IW;Kim KW;Murata M;Akazawa T;Mitsugi M
随着从哺乳动物牙齿中成功提取生长因子和骨形态发生蛋白（BMPs），许多研究人员支持使用牙源性物质开发骨替代品。一些研究还扩大了牙齿作为生长因子和干细胞载体的潜在用途。对已发表的关于牙源性再生组织工程技术的研究结果进行了概述。考虑到100多篇已发表的论文，我们的团队开发了用拔牙处理骨移植材料的方案和技术。根据目前的研究和未来需要的研究，我们可以预测支架、同质和异质牙骨移植物以及拔牙修复材料的发展。
With successful extraction of growth factors and bone morphogenic proteins (BMPs) from mammalian teeth, many researchers have supported development of a bone substitute using tooth-derived substances. Some studies have also expanded the potential use of teeth as a carrier for growth factors and stem cells. A broad overview of the published findings with regard to tooth-derived regenerative tissue engineering technique is outlined. Considering more than 100 published papers, our team has developed the protocols and techniques for processing of bone graft material using extracted teeth. Based on current studies and studies that will be needed in the future, we can anticipate development of scaffolds, homogenous and xenogenous tooth bone grafts, and dental restorative materials using extracted teeth.