The value of contrast enhanced ultrasound (CEUS) in the characterisation of patients with renal masses
The value of contrast enhanced ultrasound (CEUS) in the characterisation of patients with renal masses
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DOI：
10.3233/ch-2010-1352
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发表时间：
2010-01-01
影响因子：
2.1
通讯作者：
Dietrich, Christoph F.
中科院分区：
文献类型：
--
作者：
Ignee, Andre;Straub, Bernd;Dietrich, Christoph F.
超声检查经常偶然发现肾脏肿块。对比增强计算机断层扫描 (CECT) 被认为是首选方法。超声造影 (CEUS) 对肝脏病变的表征具有很大影响。其在肾脏肿块中的应用尚未得到全面研究。201 名患者转诊接受肾肿块手术治疗，其中 143 名患者满足纳入标准（组织学和参考方法）。基线超声和 CEUS BR1、通过手术 (89%) 或活检 (11%) 获得的组织学结果。88% 的患者有肾脏病变，其中恶性，12% 为良性病变。百分之八十患有肾细胞癌（RCC）。百分之七的病变是囊性的。两名患者通过 CEUS 从 CECT Bosniak II 分别升级为 CEUS Bosniak III。四． CEUS 可以预测恶性肿瘤，其敏感性、特异性、阳性、阴性预测值和准确度分别为 97%、45%、91%、75% 和 90%。 CEUS (CECT) 诊断出正确的分期为 83% (69%)。CEUS 在 RCC 的分期和特征方面优于 CECT，在囊性病变患者亚组中也是如此。 CEUS 可以替代 CECT e。 g。对 CECT 过敏或有禁忌症的患者。需要进行多中心研究来证实这些发现。
Renal masses are frequently incidentally found on ultrasound. Contrast enhanced computed tomography (CECT) is regarded as the method of choice. Contrast enhanced ultrasound (CEUS) has a high impact for characterisation of hepatic lesions. Its use in renal masses has been less comprehensively studied.Two hundred and one patients referred for surgical treatment of a renal mass, 143 patients fulfilling inclusion criteria (histology and reference method). Baseline ultrasound and CEUS with BR1, histology obtained by surgery (89%) or biopsy (11%).Eighty-eight percent of the patients had renal lesions which were malignant and 12% benign lesions. Eighty percent had renal cell carcinoma (RCC). Seven percent of the lesions were cystic. Two patients were upgraded by CEUS from CECT Bosniak II into CEUS Bosniak III resp. IV. CEUS could predict malignancy with a sensitivity, specificity, positive, negative predictive value and accuracy in 97%, 45%, 91%, 75%, and 90%. The correct staging was diagnosed by CEUS (CECT) in 83% (69%).CEUS was superior to CECT in the staging and characterisation of RCC, also in the subgroup of patients with cystic lesions. CEUS can replace CECT e. g. in patients with allergies or contraindications against CECT. Multicentre studies are necessary to confirm the findings.