The effect of 12 weeks of aerobic, resistance or combination exercise training on cardiovascular risk factors in the overweight and obese in a randomized trial
The effect of 12 weeks of aerobic, resistance or combination exercise training on cardiovascular risk factors in the overweight and obese in a randomized trial
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DOI：
10.1186/1471-2458-12-704
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发表时间：
2012-08-28
影响因子：
4.5
通讯作者：
Pal, Sebely
中科院分区：
文献类型：
--
作者：
Ho, Suleen S.;Dhaliwal, Satvinder S.;Pal, Sebely
背景：有证据表明，运动训练可以改善心血管疾病的危险因素。然而，目前尚不清楚健康益处是否仅限于有氧训练，或者其他运动方式，如阻力训练或组合，是否对超重和肥胖同样有效或更有效。本研究的目的是调查12周的中等强度有氧、阻力或综合运动训练是否会诱导和维持超重和肥胖成年人与不运动相比心血管风险状况、体重和脂肪减少的改善。为期12周的随机平行设计，检查不同运动方案对血脂、血糖和胰岛素空腹测量值以及体重变化的影响，脂肪量和饮食摄入量。参与者被随机分配到：第1组（对照，n = 16）;第2组（有氧，n = 15）;第3组（阻力，n = 16）;第4组（组合，n = 17）。使用一般线性模型分析数据，以评估校正基线值后各组的影响。结果：与对照组和阻力组相比，组合组的体重（-1.6%，p = 0.044）显著改善，与对照组（-4.4%，p = 0.003）和阻力组（-3%，p = 0.041）相比，总体脂显著改善。与对照组相比，在复方制剂组中观察到体脂百分比（-2.6%，p = 0.008）、腹部脂肪百分比（-2.8%，p = 0.034）和心肺适能（13.3%，p = 0.006）的显著改善。ApoB 48水平在阻力组中比对照组低32%（p = 0.04）。结论：与不运动相比，一个12周的训练计划包括阻力或组合运动，以中等强度进行30分钟，每周5天，导致超重和肥胖参与者的心血管风险状况改善。根据我们的观察，组合运动比有氧和阻力训练方式对减肥，减脂和心肺功能有更大的好处。因此，在《国家体育活动指南》中应推荐超重和肥胖成年人进行组合运动训练。该临床试验已在澳大利亚新西兰临床试验注册处（ANZCTR）注册，注册号：ACTRN 12609000684224。
Background: Evidence suggests that exercise training improves CVD risk factors. However, it is unclear whether health benefits are limited to aerobic training or if other exercise modalities such as resistance training or a combination are as effective or more effective in the overweight and obese. The aim of this study is to investigate whether 12 weeks of moderate-intensity aerobic, resistance, or combined exercise training would induce and sustain improvements in cardiovascular risk profile, weight and fat loss in overweight and obese adults compared to no exercise.Methods: Twelve-week randomized parallel design examining the effects of different exercise regimes on fasting measures of lipids, glucose and insulin and changes in body weight, fat mass and dietary intake. Participants were randomized to either: Group 1 (Control, n = 16); Group 2 (Aerobic, n = 15); Group 3 (Resistance, n = 16); Group 4 (Combination, n = 17). Data was analysed using General Linear Model to assess the effects of the groups after adjusting for baseline values. Within-group data was analyzed with the paired t-test and between-group effects using post hoc comparisons.Results: Significant improvements in body weight (-1.6%, p = 0.044) for the Combination group compared to Control and Resistance groups and total body fat compared to Control (-4.4%, p = 0.003) and Resistance (-3%, p = 0.041). Significant improvements in body fat percentage (-2.6%, p = 0.008), abdominal fat percentage (-2.8%, p = 0.034) and cardio-respiratory fitness (13.3%, p = 0.006) were seen in the Combination group compared to Control. Levels of ApoB48 were 32% lower in the Resistance group compared to Control (p = 0.04).Conclusion: A 12-week training program comprising of resistance or combination exercise, at moderate-intensity for 30 min, five days/week resulted in improvements in the cardiovascular risk profile in overweight and obese participants compared to no exercise. From our observations, combination exercise gave greater benefits for weight loss, fat loss and cardio-respiratory fitness than aerobic and resistance training modalities. Therefore, combination exercise training should be recommended for overweight and obese adults in National Physical Activity Guidelines. This clinical trial was registered with the Australian New Zealand Clinical Trials Registry (ANZCTR), registration number: ACTRN12609000684224.