AUS IN THE PREVENTION OF MAREKS-DISEASE
AUS IN THE PREVENTION OF MAREKS-DISEASE
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DOI：
10.2307/1590137
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发表时间：
1984-01-01
期刊：
影响因子：
1.4
通讯作者：
CHANG, TS
中科院分区：
文献类型：
--
作者：
CHANG, TS
氨基脲砜 (AUS) 被用作饲料添加剂，以防止实验室中感染马立克氏病 (MD) 的鸡死亡。 1日龄时感染MD病毒（5000个空斑形成单位）的小鸡从1日龄开始在饲料中添加AUS直至实验结束。 AUS 在所有测试浓度下均降低了马立克氏病引起的死亡率。接受 0.002% 水平 AUS 的鸡死亡率为 4%，接受 0.005% 水平的鸡死亡率为 9%，接受 0.01% 水平的鸡死亡率为 2%；对照组的死亡率分别为 44%、49% 和 50%。幸存雏鸡的病变减少幅度很小。当从饲料中去除 AUS 后，MD 引起的死亡率在 2 周内增加；平均体重也下降。
Aminoureidosulfone (AUS) was used as a feed additive to prevent mortality in Marek''s disease (MD)-infected chickens in the laboratory. Chicks infected with MD virus (5000 plaque-forming units) at 1 day of age were given AUS in the feed from 1 day of age until the experiment was terminated. AUS, at all concentrations tested, reduced mortality due to Marek''s disease. Chickens receiving AUS at the 0.002% level had a 4% mortality rate, those receiving 0.005% had 9% mortality and those receiving 0.01% had 2% mortality; mortality rates in the respective controls were 44, 49 and 50%. Lesion reduction in surviving chicks was minimal. When AUS was withdrawn from the feed, MD-induced mortality increased within 2 wk; average body wt decreased also.