Asymmetric Protonation of Enolates
Asymmetric Protonation of Enolates
复制标题
烯醇化物的不对称质子化
DOI：
10.1002/anie.199014201
复制
发表时间：
1990
影响因子：
--
通讯作者：
J. Rebek
中科院分区：
文献类型：
--
作者：
D. Potin;K. Williams;J. Rebek
[2] 方法。在70℃下，向CuBr(670mg，3mmol)在乙醇/丙酮(I：1 viv)混合物(25mL)中的溶液中添加ddtp(840mg，3mmol)在沸腾乙醇/丙酮(I：1vpj混合物(30mL))中的溶液。很快溶液变成乳状，透明晶体开始分离。通过倾析收集晶体。用乙醚洗涤，产量：550mg(65%)。131 方法：在氮气氛下，将CuBr(390mg，2.72mmol)在5mL乙醇/乙腈(1.2v/v)混合物中的温热溶液添加到ddtp(380mg，1.36mmol)在5mL甲醇中的温热溶液中，通过过滤收集晶体，用乙醚洗涤，并干燥。空气中产量：540 mg（70% Cu）。
[2] Method. To a solution of CuBr,(670 mg. 3 mmol) in an ethanol/acetone (I: 1 viv) mixture (25 mL) at 70'C was added a solution of ddtp (840 mg, 3 mmol) in a boiling ethanol/acetone (I: 1 vpj mixture (30 mL). Soon the solution turned milky and transparant crystals started to separate. The crystals were collected by decantation. washed with ether, and dried in air. Yield: 550mg (65%).131 Method: Under a nitrogen atmosphere a warm solution of CuBr (390 mg. 2.72 mmol), in a 5 mL ethanol/acetonitrile (1.2 v! v) mixture, was added to a warm solution of ddtp (380 mg, 1.36 mmol) In 5 mL methanol. The crystals were collected by filtation, washed with ether, and dried in air. Yield: 540 mg (70% Cu).