Autoantibodies can be prognostic markers of an erosive disease in early rheumatoid arthritis

Autoantibodies can be prognostic markers of an erosive disease in early rheumatoid arthritis
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DOI:
10.1136/ard.62.5.427
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发表时间:
2003-05-01
影响因子:
27.4
通讯作者:
Ruzicková, S
Ruzicková, S
中科院分区:
医学1区
文献类型:
--
作者:
Vencovsky, J;Machácek, S;Ruzicková, S

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目标:评估选定的实验室参数对预测早期类风湿性关节炎(RA)患者进行性和侵蚀性发展的贡献。方法:在一项前瞻性研究中,通过酶联免疫吸附试验(ELISA)测量了104名RA患者的环瓜氨酸肽(抗CCP)抗体、类风湿因子(RF)的基线水平
Objective: To evaluate a contribution of selected laboratory parameters for a prediction of progressive and erosive development in patients with early rheumatoid arthritis (RA).Methods: In a prospective study baseline levels of antibodies to cyclic citrullinated peptide (anti-CCP), IgM, IgA, and IgG rheumatoid factors (RFs) were measured by enzyme linked immunosorbent assay (ELISA) in 104 patients with RA with disease duration