Color M-mode flow propagation velocity versus conventional Doppler indices in the assessment of diastolic left ventricular function in patients on chronic hemodialysis
Color M-mode flow propagation velocity versus conventional Doppler indices in the assessment of diastolic left ventricular function in patients on chronic hemodialysis
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DOI：
10.1046/j.1540-8175.2002.00467.x
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发表时间：
2002-08-01
影响因子：
1.5
通讯作者：
Ahmad, M
中科院分区：
文献类型：
--
作者：
Chamoun, AJ;Xie, TR;Ahmad, M
背景和目的：彩色M型血流传播速度（Vp）已被报道为舒张功能的前负荷无关的措施。为了研究负荷条件对慢性血液透析患者舒张功能评估的影响，我们测量了透析前后的Vp和常规多普勒指数。研究方法：对20例收缩功能正常的血液透析患者在透析前后测定Vp、早期充盈速度（E）、E减速时间（DT）、心房收缩速度（A）、等容舒张时间（IVRT）和肺心房血流逆转速度（PFR）。12名健康对照者接受了相同的测量。结果如下：血液透析患者基线Vp显著低于正常对照组，而E/A、DT、IVRT和肺血流逆转无显著差异。E、IVRT和PFR受血液透析的影响，而彩色M型血流传播速度、A和DT不受血液透析的影响。结论：彩色M型血流传播速度似乎是慢性血液透析患者舒张功能的一个前负荷独立的措施，其中孤立性舒张功能障碍似乎普遍存在。
Background and Objective: Color M-mode flow propagation velocity (Vp) has been reported as a preload-independent measure of diastolic function. To study the effects of loading conditions on diastolic function assessment in patients on chronic hemodialysis, we measured Vp and conventional Doppler indices pre- and posthemodialysis. Methods: Twenty hemodialysis patients with normal systolic function underwent measurement of Vp, early filling velocity (E), its deceleration time (DT), atrial contraction velocity (A), isovolumic relaxation time (IVRT), and pulmonary atrial flow reversal velocity (PFR) pre- and posthemodialysis. Twelve healthy controls underwent these same measurements. Results: Hemodialysis patients had significantly slower Vp at baseline than normal controls, while E/A, DT, IVRT, and pulmonary flow reversal were not significantly different. E, IVRT, and PFR were affected by hemodialysis, while color M-mode flow propagation velocities, A and DT were not. Conclusions: Color M-mode flow propagation velocity seems to be a preload-independent measure of diastolic function in chronic hemodialysis patients in whom isolated diastolic dysfunction appears prevalent.