Influence of the SARS-CoV-2 Outbreak on the Uptake of a Popular Smoking Cessation App in UK Smokers: Interrupted Time Series Analysis

Influence of the SARS-CoV-2 Outbreak on the Uptake of a Popular Smoking Cessation App in UK Smokers: Interrupted Time Series Analysis
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DOI:
10.2196/19494
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发表时间:
2020-06-11
影响因子:
5
通讯作者:
Brown, Jamie
Brown, Jamie
中科院分区:
医学2区
文献类型:
--
作者:
Perski, Olga;Herbec, Aleksandra;Brown, Jamie

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背景:严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的爆发可能会促使更多的吸烟者尝试戒烟。然而,鉴于英国停止吸烟服务和vape商店的暂时关闭,试图戒烟的吸烟者可能会转而寻求移动的健康支持,如智能手机apps.Objective:我们使用中断的时间序列方法研究了SARS-CoV-2爆发是否与英国其他流行戒烟应用程序Smoke Free下载量的阶跃变化或增加趋势相关。数据来自英国每日和非每日吸烟的成年吸烟者,他们在2020年1月1日至2020年3月31日(主要分析)和2019年1月1日至2020年3月31日(次要分析)之间下载了Smoke Free应用程序。结果变量是在12小时(主要分析)或每日水平(次要分析)汇总的下载次数。解释变量是SARS-CoV-2爆发的开始时间,分别为2020年3月1日(主要分析)和2020年1月15日(次要分析)。调整相关协变量的广义加性混合模型fitted.Results:收集了45,105(主要分析)和119,881(次要分析)用户的数据。在这两项分析中,没有证据表明SARS-CoV-2爆发的开始导致下载量的阶跃变化或增加趋势。贝叶斯因子(BFs)的计算表明,与大关联相比,主要分析的数据支持零假设(对于水平,BF=0.25;对于斜率,BF=0.26),但对小关联的检测不敏感(对于水平,BF=0.78;对于斜率,BF= 1.35)。在英国,在2020年1月1日至2020年3月31日期间,以及在2019年1月1日至2020年3月31日期间,没有证据表明SARS-CoV-2爆发与流行戒烟应用程序下载量的大幅变化或增加趋势有关。2起暴发呈小的阶跃变化或上升趋势,尚无定论。
Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak may motivate smokers to attempt to stop in greater numbers. However, given the temporary closure of UK stop smoking services and vape shops, smokers attempting to quit may instead seek out mobile health support, such as smartphone apps.Objective: We examined, using an interrupted time series approach, whether the SARS-CoV-2 outbreak has been associated with a step change or increasing trend in UK downloads of an otherwise popular smoking cessation app, Smoke Free.Methods: Data were from daily and nondaily adult smokers in the United Kingdom who had downloaded the Smoke Free app between January 1, 2020, and March 31, 2020 (primary analysis), and January 1, 2019, and March 31, 2020 (secondary analysis). The outcome variable was the number of downloads aggregated at the 12-hourly (primary analysis) or daily level (secondary analysis). The explanatory variable was the start of the SARS-CoV-2 outbreak, operationalized as March 1, 2020 (primary analysis), and January 15, 2020 (secondary analysis). Generalized additive mixed models adjusted for relevant covariates were fitted.Results: Data were collected on 45,105 (primary analysis) and 119,881 (secondary analysis) users. In both analyses, there was no evidence for a step change or increasing trend in downloads attributable to the start of the SARS-CoV-2 outbreak. Calculation of Bayes factors (BFs) indicated that the data for the primary analysis favored the null hypothesis compared with large associations (for level, BF=0.25; for slope, BF=0.26) but were insensitive to the detection of small associations (for level, BF=0.78; for slope, BF= 1.35).Conclusions: In the United Kingdom, between January 1, 2020, and March 31, 2020, and between January 1, 2019, and March 31, 2020, there was no evidence that the SARS-CoV-2 outbreak has been associated with a large step change or increasing trend in downloads of a popular smoking cessation app. Findings on the association of the SARS-CoV-2 outbreak with a small step change or increasing trend were inconclusive.