Barriers to black women's participation in cancer clinical trials.
Barriers to black women's participation in cancer clinical trials.
复制标题
黑人女性参与癌症临床试验的障碍。
DOI：
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发表时间：
1997
影响因子：
3.3
通讯作者：
Mark S. Johnson
中科院分区：
文献类型：
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作者：
Charles P. Mouton;Sonja Harris;S. Rovi;Patty Solorzano;Mark S. Johnson
这项研究调查了可能阻碍黑人女性参与癌症研究的态度。研究对象是从那些未对妇女健康倡议的初次招募邮件做出回应的女性中招募的。对每位研究对象进行了一次7到10分钟的电话调查。80名研究对象中有三分之一（29人）是黑人。56%的黑人女性和71%的白人女性对癌症临床试验持积极态度。超过80%的受访女性同意临床研究有益于社会并能增加医学知识。然而，近三分之一的黑人女性认为科学家不可信，而只有4%的白人有类似反应。此外，29%的黑人女性认为研究人员不关心她们，相比之下，只有14%的白人女性有此看法。只有28%的黑人女性认为美国的临床研究是合乎道德的，并且37%的黑人女性更倾向于由黑人科学家治疗，而白人中只有2%有此偏好。在控制其他协变量后，黑人女性总体上对临床试验的态度比白人女性更消极。这些发现支持了黑人和其他少数族裔参与临床研究存在障碍的可能性。这些障碍可能会影响黑人女性参与癌症临床试验。提高信任度以及让研究人员给人一种关心的印象，对于克服这些障碍至关重要。让更多黑人科学家作为癌症临床试验的领导者，也可能有助于提高这些参与率。
This study examines attitudes that may deter black women from participating in cancer research. Subjects were recruited from women who did not respond to the initial recruitment mailing for the Women's Health Initiative. Each subject was administered a 7- to 10-minute telephone survey. One third (29) of the 80 subjects were black. Fifty-six percent of black women and 71% of white women had positive attitudes toward cancer clinical trials. More than 80% of the women surveyed agreed that clinical research benefits society and increases medical knowledge. However, almost one third of the black women agreed that scientists cannot be trusted while only 4% of whites responded similarly. Additionally, 29% of black women agreed that researchers did not care about them compared with 14% of white women. Only 28% of black women felt that clinical research in the United States was ethical, and 37% had a preference to be treated by a black scientist compared with 2% of whites. Controlling for other covariates, black women had more negative altitudes overall to clinical trials than white women. These findings support the likelihood that barriers exist for the participation of blacks and other minorities in clinical research. These barriers may impact the involvement of black women in cancer clinical trials. Improving trust and creating a perception of a caring attitude from investigators are important to overcoming these barriers. The inclusion of more black scientists as leaders of cancer clinical trials also may help improve these participation rates.