Monoamines and sleep: microdialysis findings in pons and amygdala
Monoamines and sleep: microdialysis findings in pons and amygdala
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DOI：
10.1016/s0006-8993(00)02013-8
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发表时间：
2000-03-31
期刊：
影响因子：
2.9
通讯作者：
Farber, PR
中科院分区：
文献类型：
--
作者：
Shouse, MN;Staba, RJ;Farber, PR
这是第一份比较猫蓝斑复合体（LC）和杏仁核中去甲肾上腺素（NE）、5-羟色胺（5-HT）和多巴胺（DA）浓度（pg/μ l）的微透析报告。NE和5-HT从清醒到慢波睡眠（SWS）再到快动眼睡眠（REM）呈进行性下降。DA的浓度在整个睡眠-觉醒周期的任何一个采集点都没有变化。我们的结论是NE和5-HT的释放调节与睡眠-觉醒周期相关的生理成分，但DA没有。(C)2000 Elsevier Science B. V.保留所有权利。
This is the first microdialysis report comparing concentrations (pg/mu l) of norepinephrine (NE), serotonin (5-HT) and dopamine (DA) derived from feline locus ceruleus complex (LC) and amygdala. NE and 5-HT declined progressively from waking to slow-wave-sleep (SWS) and then to rapid-eye-movement (REM) sleep. Concentrations of DA did not change at either collection site across the sleep-wake cycle. We conclude that release of NE and 5-HT release modulates physiologic components related to the sleep-wake cycle, but DA does not. (C) 2000 Elsevier Science B.V. All rights reserved.