A database of immunoglobulins with integrated tools: DIGIT.

A database of immunoglobulins with integrated tools: DIGIT.
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DOI:
10.1093/nar/gkr806
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发表时间:
2012-01
影响因子:
14.9
通讯作者:
Marcatili P
Marcatili P
中科院分区:
生物学2区
文献类型:
--
作者:
Chailyan A;Tramontano A;Marcatili P

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DIGIT(带有集成工具的免疫球蛋白数据库)数据库 (http://biocomputing.it/digit) 是一个集成资源,存储带注释的免疫球蛋白可变结构域序列,并包含用于搜索和分析它们的工具。数据库中的注释包括有关抗原类型、各自种系序列以及轻链和重链之间的配对信息的信息。其他注释,例如互补性决定区的识别、其结构类别的分配以及相对于种系的突变的识别,都是动态计算的,也可以针对用户提交的序列获得。该系统允许执行定制的 BLAST 搜索和自动构建域的 3D 模型。
The DIGIT (Database of ImmunoGlobulins with Integrated Tools) database (http://biocomputing.it/digit) is an integrated resource storing sequences of annotated immunoglobulin variable domains and enriched with tools for searching and analyzing them. The annotations in the database include information on the type of antigen, the respective germline sequences and on pairing information between light and heavy chains. Other annotations, such as the identification of the complementarity determining regions, assignment of their structural class and identification of mutations with respect to the germline, are computed on the fly and can also be obtained for user-submitted sequences. The system allows customized BLAST searches and automatic building of 3D models of the domains to be performed.
DOI: 10.1016/s0022-2836(05)80102-0
发表时间: 1990-09-05
影响因子: 5.6
作者:
TRAMONTANO, A;CHOTHIA, C;LESK, AM
通讯作者: LESK, AM
DOI: 10.1016/0022-2836(87)90412-8
发表时间: 1987-08-20
影响因子: 5.6
作者:
CHOTHIA, C;LESK, AM
通讯作者: LESK, AM
DOI: 10.1093/protein/3.6.531
发表时间: 1990-05-01
期刊: PROTEIN ENGINEERING
影响因子: --
作者:
SOLLAZZO, M;CASTIGLIA, D;ZANETTI, M
通讯作者: ZANETTI, M
DOI: 10.1093/nar/gkj088
发表时间: 2006-01-01
影响因子: 14.9
作者:
Giudicelli, Veronique;Duroux, Patrice;Ginestoux, Chantal;Folch, Geraldine;Jabado-Michaloud, Joumana;Chaume, Denys;Lefranc, Marie-Paule
通讯作者: Lefranc, Marie-Paule
DOI: 10.1006/jmbi.1997.1354
发表时间: 1997-11-07
影响因子: 5.6
作者:
AlLazikani, B;Lesk, AM;Chothia, C
通讯作者: Chothia, C