PRIMARY APPLICATION OF MICRO-FLOW IMAGING TECHNOLOGY IN THE DIAGNOSIS OF HEPATIC TUMORS
PRIMARY APPLICATION OF MICRO-FLOW IMAGING TECHNOLOGY IN THE DIAGNOSIS OF HEPATIC TUMORS
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微流成像技术在肝肿瘤诊断中的初步应用
DOI：
10.1016/j.ultrasmedbio.2018.09.025
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发表时间：
2019-02-01
影响因子：
2.9
通讯作者：
Wang, Wenping
中科院分区：
文献类型：
--
作者：
Han, Hong;Ding, Hong;Wang, Wenping
本研究的目的是用新发布的无造影剂微流成像（MFI）技术评价肝脏局灶性病变的血管结构。本研究入组了80例肝肿瘤患者。显示的血流的丰富程度首先与彩色多普勒血流成像进行比较，根据Adler的方法使用等级。结果表明，MFI优于彩色多普勒血流显像，有显著性差异（p <0.0001）。以超声造影动脉期的增强位置为基础，进一步评价MFI显示的肿瘤内血流分布。MFI与超声造影诊断符合率为73.75%（59/80），明显高于彩色多普勒血流显像（52.5%，42/80）（p <0.0001）。此外，对于5例局灶性结节性增生，MFI清楚地显示了轮辐轮或放射状瘤内血管，这是诊断局灶性结节性增生的特异性发现。(C)2018由Elsevier Inc.出版代表世界超声波医学与生物学联合会。
The purpose of the study was to evaluate the vascular architecture of focal liver lesions with the newly released non-contrast micro-flow imaging (MFI) technique. Eighty patients with 80 hepatic tumors were enrolled in this study. The richness of displayed blood flow was first compared with color Doppler flow imaging using grades according to Adler's method. The results indicated that MFI outperformed color Doppler flow imaging with a statistically significant difference (p < 0.0001). With the enhanced position in arterial phase of contrast-enhanced ultrasound imaging as the ground truth, the displayed blood flow distribution within tumors in MFI was further evaluated. The coincidence rate between MFI and contrast-enhanced ultrasound was 73.75% (59/80), which was higher than that of color Doppler flow imaging (52.5%, 42/80) (p < 0.0001). Moreover, for the five cases of focal nodular hyperplasia, MFI clearly revealed the spoke-wheel or radiating intra-tumoral vasculature, a finding specific to the diagnosis of focal nodular hyperplasia. (C) 2018 Published by Elsevier Inc. on behalf of World Federation for Ultrasound in Medicine & Biology.