Myocardial Deformation Pattern Differs between Ischemic and Non-ischemic Dilated Cardiomyopathy: The Diagnostic Value of Longitudinal Strains
Myocardial Deformation Pattern Differs between Ischemic and Non-ischemic Dilated Cardiomyopathy: The Diagnostic Value of Longitudinal Strains
复制标题
缺血性和非缺血性扩张型心肌病的心肌变形模式不同：纵向应变的诊断价值
DOI：
10.1016/j.ultrasmedbio.2019.10.006
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发表时间：
2020
影响因子：
2.9
通讯作者：
Wang Dao Wen
中科院分区：
文献类型：
--
作者：
Zuo Houjuan;Zhang Yan;Ma Fei;Li Rui;Wang Yan;Li Chenze;Wang Hong;Wang Dao Wen
缺血性心肌病（ICM）和非缺血性心肌病（NICM）都以左心室功能障碍和扩张为特征。区分ICM和NICM使用非侵入性图像模式是一个临床挑战。本研究采用二维斑点跟踪超声心动图（2d STE）比较了ICM和NICM的心肌变形模式，并寻求对扩张型心肌病的诊断和治疗有价值的参数。研究人群包括84例连续患者，左室舒张末期尺寸>55 mm，射血分数（EF） 50%和<70%)对NICM的整体纵向应变没有显著影响。综上所述，NICM患者的左室扩张和收缩功能障碍、相对根尖保留和左室纵向应变的基础恶化模式在2-D STE中观察到，而非ICM。中、尖纵向应变与基底应变之和的比值可以作为NICM与ICM的鉴别指标。
Both ischemic cardiomyopathy (ICM) and non-ischemic cardiomyopathy (NICM) are characterized by left ventricular (LV) dysfunction and dilation. Differentiation between ICM and NICM using non-invasive image modalities is a clinical challenge. This study compared the myocardial deformation patterns of ICM and NICM using 2-D speckle tracking echocardiography (2-D STE) and sought to find parameters valuable in the diagnosis and management of dilated cardiomyopathy. The study population comprised 84 consecutive patients with LV end-diastolic dimension >55 mm and ejection fraction (EF) 50% and <70%) had no significant influence on global longitudinal strain in NICM. In conclusion, LV dilation and systolic dysfunction, relative apical sparing and a basal worsening pattern of LV longitudinal strain by 2-D STE were observed in patients with NICM but not ICM. The ratio of basal to sum of mid- and apical longitudinal strains could help differentiate NICM from ICM.