Factors associated with surgical and radiation therapy for early stage breast cancer in older women
Factors associated with surgical and radiation therapy for early stage breast cancer in older women
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DOI：
10.1093/jnci/88.11.716
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发表时间：
1996-06-05
影响因子：
10.3
通讯作者：
Kessler, LG
中科院分区：
文献类型：
--
作者：
BallardBarbash, R;Potosky, AL;Kessler, LG
背景：据报道，除了与人口和医疗保健相关的特征外，乳腺癌诊断时女性的年龄和生理状况也会影响标准治疗的接受。以前关于年龄和合并症影响的研究没有检查其他与患者、地区或医疗保健相关的特征是否改变了年龄和合并症与接受的治疗类型的关联。目的：本研究对1985年至年间确诊的18704例65岁以上乳腺癌患者进行保乳手术和放射治疗的相关因素分析。方法：使用一个数据文件，将医疗保险索赔记录与美国国家癌症研究所监测、流行病学和最终结果(SEER)计划的数据联系起来。Logistic回归分析用于检查患者、地区和医院特征与接受特定治疗之间的关系。似然性检验被用来评估观察到的相关性的重要性(表示为优势比[OR])。由于多重比较，只有那些具有双边P值的OR
Background: In addition to demographic and health care-related characteristics, the age and physiologic status of women at the time of breast cancer diagnosis have been reported to influence receipt of standard treatments. Previous studies of the influence of age and comorbidity have not examined whether other patient-, region-, or health care-related characteristics altered the association of age and comorbidity with type of treatment received. Purpose: This study examined factors associated with receipt of breast-conserving surgery and radiation therapy, both of which are recommended treatments for breast cancer, among a cohort of 18 704 women aged 65 years or more who had breast cancer diagnosed during the period from 1985 through 1989. Methods: A data file linking Medicare claims records to data from the Surveillance, Epidemiology, and End Results (SEER) Program of the U.S. National Cancer Institute was utilized. Logistic regression analysis was used to examine associations between patient, region, and hospital characteristics and the receipt of specific treatments. The likelihood test was used to assess the significance of observed associations (expressed as odds ratios [ORs]). Because of multiple comparisons, only those ORs with two-sided P values