Interactive effects of food deprivation and exercise on reproductive function in female hamsters.
Interactive effects of food deprivation and exercise on reproductive function in female hamsters.
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食物匮乏和运动对雌性仓鼠生殖功能的交互影响。
DOI：
10.1152/ajpregu.1994.267.1.r185
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发表时间：
1994
期刊：
影响因子：
--
通讯作者：
Wade,GN
中科院分区：
文献类型：
--
作者：
Powers,JB;Jetton,AE;Wade,GN
两个实验评估了食物剥夺和转轮访问对雌性仓鼠发情周期和发情行为的联合影响。在实验1中，在发情周期的第1天和第2天的食物剥夺扰乱了下一次预期的排卵，这种影响在被剥夺时允许在跑步轮上锻炼的女性中更强，而不是更弱。在实验2中，使用类似的方案，除了雌性动物被切除卵巢并接受苯甲酸雌二醇的顺序注射（EB; 5微克）和孕酮（P; 200微克），间隔48小时诱导脊柱前凸，在P后4-5小时进行测试。食物剥夺伴随激素治疗减少了脊柱前凸持续时间，但这种影响仅在允许在活动轮中跑步的女性中显着。先前的研究结果表明，获得运行轮衰减的抑制作用，短的光周期暴露对仓鼠发情周期。与此相反，目前的结果表明，这种相同的操作夸大，而不是减少食物剥夺对发情周期和发情诱导的行为发情的抑制作用。
Two experiments evaluated the combined effects of food deprivation and runningwheel access on estrous cycles and estrous behavior of female hamsters. In experiment 1, food deprivation on days 1 and 2 of the estrous cycle disrupted the next expected ovulation, and this effect was more, rather than less, robust in females allowed to exercise in running wheels while they were deprived. In experiment 2, a similar protocol was used except the females were ovariectomized and received sequential injections of estradiol benzoate (EB; 5 micrograms) and progesterone (P; 200 micrograms) separated by 48 h to induce lordosis, which was tested 4-5 after P. Food deprivation concomitant with hormonal treatment diminished lordosis durations, but this effect was significant only among the females that were permitted to run in activity wheels. Previous findings demonstrated that access to running wheels attenuated the inhibitory effects of short photoperiod exposure on hamster estrous cycles. In contrast, the present results indicate that this same manipulation exaggerates rather than diminishes the inhibitory effects of food deprivation on estrous cycles and hormone-induced behavioral estrus.