Resting energy expenditure in manic episode
Resting energy expenditure in manic episode
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DOI：
10.1111/j.1399-5618.2008.00649.x
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发表时间：
2009-02-01
影响因子：
5.4
通讯作者：
Altiay, Gundeniz
中科院分区：
文献类型：
--
作者：
Caliyurt, Okan;Altiay, Gundeniz
我们的目的是评估双相I型障碍、躁狂发作患者的静息能量消耗。纳入了42名在特拉基亚大学医院住院精神病学诊所接受治疗并符合必要研究标准的双相I型障碍、躁狂发作患者，沿着27名对照。采用DSM-IV诊断标准和Bech-Rafaelsen躁狂量表评定患者躁狂发作的诊断和严重程度。用间接测热仪测定静息能量消耗值，发现躁狂症患者的静息能量消耗值高于对照组。对照组显示体重指数和静息能量消耗之间存在显著相关性，但躁狂患者没有表现出类似的相关性。Bech-Rafaelsen躁狂评定量表评分与躁狂患者静息能量消耗值之间也无相关性，我们发现双相I型障碍、躁狂发作患者静息能量消耗值显著增加。这些结果表明，静息能量消耗的评估双相I型躁狂发作的可能临床用途，也建议静息能量消耗作为一个可能的生物标志物。
We aimed to assess the resting energy expenditure in bipolar I disorder, manic episode patients.Forty-two bipolar I disorder, manic episode patients that were treated in the inpatient psychiatry clinic of Trakya University Hospital and had met the necessary study criteria were included along with 27 controls. DSM-IV criteria and the Bech-Rafaelsen Mania Rating Scale were used to evaluate patients' diagnosis and severity of the manic episodes. The indirect calorimetry device was used to measure resting energy expenditure values.Resting energy expenditure values of manic patients were found to be higher than those of the controls. Controls showed significant correlations between body mass index and resting energy expenditure, but manic patients did not exhibit similar correlations. There was also no relation between Bech-Rafaelsen Mania Rating Scale scores and resting energy expenditure values in manic patients.We found significantly increased resting energy expenditure values in bipolar I disorder, manic episode patients. These findings suggest a possible clinical use of resting energy expenditure for evaluation of bipolar I disorder manic episode and also suggest resting energy expenditure as a possible biological marker.